Since the apoE4 allele is a risk factor or susceptibility gene in late-onset familial and sporadic AD, the mechanism of disease expression may involve metabolic effects that are isoform specific. Isoform-specific interactions of apoE therefore become critical in the mechanism of AD pathogenesis. Detailed characterization of the binding of the apoE isoforms with proteins and peptides relevant to the pathology of the disease may be critical in understanding disease pathogenesis. These critic...

Freud's Philosophy of the Unconscious is the only comprehensive, systematic study of Sigmund Freud's philosophy of mind. Freud emerges as a sophisticated philosopher who addresses many of the central questions that concern contemporary philosophers and cognitive scientists while anticipating many of their views. While still a student in Vienna, Freud was initiated into philosophy by Franz Brentano. The book charts Freud's intellectual development as he deals with the mind-body pro...

It’s an Urban Style of Love is a collection of short urban tales depicting how contemporary love is found where you least expect it.From online gaming to jogging, the club scene to the park, these short stories inspire us to believe that there is someone for everyone, and sometimes you will find what your heart desires most, in the most unexpected places.It’s an Urban Style of Love features sixteen urban tales from fifteen of our favorite contemporary writers.

Reproductive technology allows us to test embryos' genes before deciding whether to transfer them to a woman's uterus. Embryo selection raises many ethical questions but is virtually unregulated in the United States. This comprehensive study considers the ethical, medical, political, and economic aspects of developing appropriate regulation.

A trailblazing philosopher’s exploration of the latest brain science—and its ethical and practical implications.What happens when we accept that everything we feel and think stems not from an immaterial spirit but from electrical and chemical activity in our brains? In this thought-provoking narrative—drawn from professional expertise as well as personal life experiences—trailblazing neurophilosopher Patricia S. Churchland grounds the philosophy of mind in the essential ingredients...

How will increased understanding of the human genome affect our ability to diagnose and treat disease? The subject of recombinant DNA technology is no longer limited to the research laboratory; it is being discussed in ever-widening medical circles. Introduction to Molecular Medicine is especially written for the physician who is not a genetics expert but wishes to understand this new science and find entry to the more specialized publications. The first chapters present t...

Complementary and alternative medicine encompasses a wide range of modalities, including acupuncture, herbs and supplements, naturopathy, and body and mind therapies. The use of these healing methods is increasing rapidly, and more and more patients are approaching primary care physicians with questions about them. The purpose of this issue is to help doctors understand the evidence supporting and refuting complementary and alternative medicine techniques so they can provide patients with ...

'if AI is outside your field, or you know something of the subject and would like to know more then Artificial Intelligence: The Basics is a brilliant primer.' - Nick Smith, Engineering and Technology Magazine November 2011Artificial Intelligence: The Basics is a concise and cutting-edge introduction to the fast moving world of AI. The author Kevin Warwick, a pioneer in the field, examines issues of what it means to be man or mac...

A Times Higher Education Book of the Week Judith Butler elucidates the dynamics of public assembly under prevailing economic and political conditions, analyzing what they signify and how. Understanding assemblies as plural forms of performative action, Butler extends her theory of performativity to argue that precarity—the destruction of the conditions of livability—has been a galvanizing force and theme in today’s highly visible protests. “Butler’s book is everything that a book ...

Everybody is aware, all seven billion of us. We are aware of thoughts, feelings, sensations, and perceptions. All people share the experience of being aware, but relatively few people are aware that they are aware. Most people’s lives consist of a flow of thoughts, images, ideas, feelings, sensations, sights, sounds, and so on. Very few people ask, 'What is it that knows this flow of thoughts, feelings, and perceptions? With what am I aware of my experience?'The knowing of our bein...

Atlas of Dermatology in Internal Medicine is the only concise text-atlas to cover the most common and most important cutaneous manifestations of systemic disease in children and adults. It features more than 150 clinical photographs that are accompanied by format-driven, clinically focused text on the diagnosis and management of cutaneous manifestations of connective tissue, pulmonary, renal, GI, endocrine, malignant, infectious, and HIV disease. There is also a separate chapter o...

A Buddhist monk and esteemed neuroscientist discuss their converging—and diverging—views on the mind and self, consciousness and the unconscious, free will and perception, and more.Buddhism shares with science the task of examining the mind empirically; it has pursued, for two millennia, direct investigation of the mind through penetrating introspection. Neuroscience, on the other hand, relies on third-person knowledge in the form of scientific observation. In this...