From a lunar base, Lisä and a group of Renaissance officers observe an Ouröbörös ship parked in space near Mars. But it's a serious threat to the solar system, and also to planet Earth. This is the impatiently awaited new album of a series that become a veritable benchmark for comic lovers.

History is made with the first human expedition to another galaxy, under the guidance of Renaissance. Meanwhile, back on Earth, Liz explores the foothills of the Andes in a desperate search for Swänn, hoping to find him in one piece. An ocean away, in London, Hélène and Sätie follow the trail of a forbidden experiment: the creation of human-Näkän hybrids. Three expeditions, three paths that will lead to the discovery of the greatest threat ever orchestrated against humanity and Renaissance...