What does it take for warnings about violent conflict and war to be listened to, believed and acted upon? Why are warnings from some sources noticed and largely accepted, while others are ignored or disbelieved? These questions are central to considering the feasibility of preventing harm to the economic and security interests of states. Challenging conventional accounts that tend to blame decision-makers' lack of receptivity and political will, the authors offer a new theoretical framewor...

This Recent Results in Cancer Research volume provides an up-to-date overview of the multidisciplinary management of locally confined rectal cancer as well as colorectal cancer with synchronous resectable liver metastases. The contents comprise the majority of the invited contributions from the Second St. Gallen EORTC Gastrointestinal Cancer Conference, held on 6-8 March 2014 in St. Gallen, Switzerland. Written by some of the world’s leading experts in the imaging, endoscopy, pathology, mo...

The conditions of Crohn’s disease and ulcerative colitis are excellent examples of how the exponential growth of knowledge in biomedical science can make a remarkable impact on clinical practice and patient’s quality of life. It has led to the development of unique novel immunomodulatory treatments. These are continuously being refined to treat not only the two original conditions in the gut, but the systemic immunologic illness with its associated extraintestinal disorders. New therapies ...

Radiation Oncology provides residents, fellows, and clinicians with a practical, evidence-based guide to the current management of difficult cases in radiation oncology. Emphasis is on the management of those clinical challenges commonly seen in practice that the community practitioner would normally handle without outside referral. The book offers comparisons of treatment approaches to difficult situations, allowing the reader to compare their current treatment approach to that o...

This book offers a complete overview on non colorectal non neuroendocrine (NCRNNE) liver metastases and describes in detail the currently available therapies. Each chapter focuses on the treatment of metastases from a particular primary malignancy and also provides valuable information on incidence, natural history and diagnosis. NCRNNE liver metastases are rare entities compared with colorectal and neuroendocrine metastases, for which the treatments are well codified. While more publicati...

This book aims to provide an up-to-date review of the literature in each of the major areas relating to the management of older urological cancer patients, and makes recommendations for best practice and future research. The authors come from a broad geographic spread including the UK, mainland Europe and North America to ensure a worldwide relevance.

This book provides a thorough and up-to-date discussion of key issues in the supportive care of children with cancer. A variety of frequently encountered situations is covered, including infections, metabolic, cardiopulmonary and neurologic emergencies, tumor lysis syndrome, pain, emesis, mucositis, thrombotic disorders, nutritional problems, hyperleukocytosis and acute abdomen. Throughout the emphasis is firmly on evidenced-based guidance developed from the relevant literature. Informatio...

Melanoma is a concise handbook that identifies best-practice guidelines and presents the most current procedures for the diagnosis and management of melanoma in a succinct and easy-to-read manner. Chapters cover melanoma pathology, biopsy techniques, staging and risk stratification, surgical treatment of localized melanoma, immunotherapy, radiation therapy, and guidelines for resected melanoma, targeted therapy, cytotoxic chemotherapy, and management of brain metastases, mucosal a...

Over the past decade, major advances have occurred in the management of the many fields of cancer treatment encountered by the general surgeon. These developments have evolved from improved understanding of disease biology, high level clinical outcomes studies, as well as translational research with new available therapies. These advances have brought major changes to cancer care and have surfaced new dilemmas in clinical decision-making. Modern cancer management requires an understanding ...

Though kidney transplantation is considered a routine procedure, there are still significant challenges in post-transplant management. Core Concepts in Renal Transplantation is a clinically focused authoritative guide to the management of kidney transplantation. This comprehensive, state-of-the-art reference summarizes the recent changes in the field of transplantation, offering the complete range of up-to-date information on all the various aspects of basic immunobiology and the ...

This book is a rich source of information on point-of-care (POC) tests for the diagnosis and treatment of severe hemorrhage, including thromboelastography, thromboelastometry, heparin monitoring systems, and platelet function analyzers (Multiplate, PFA-100, VerifyNow, etc.). The opening chapters focus on the pathophysiology of coagulation and the general characteristics of POC devices. The relevance of POC tests in specific scenarios is then carefully explained, with guidance on their use ...

In 2011, the General Surgical Oncology Fellowship Program at the University of Toronto sought to develop a practical approach to common oncology problems faced by general surgeons. This was a collaboration between current and previous fellows, as well as staff at the University of Toronto, including experts from Princess Margaret Cancer Centre, Odette Cancer Centre (at Sunnybrook Health Sciences Centre), Mount Sinai Hospital, Toronto General Hospital, St. Michael’s Hospital, and St. Joseph...