Covering computational tools in drug design using techniques from chemoinformatics, molecular modelling and computational chemistry, this book explores these methodologies and applications of in silico medicinal chemistry. The first part of the book covers molecular representation methods in computing in terms of chemical structure, together with guides on common structure file formats. The second part examines commonly used classes of molecular descriptors. The third part provides a guide...

A look into the paranormal legends, lore, mythology, and monsters featured on the hit television show Supernatural.From angels to demons, The Mythology of Supernatural explores the religious roots and the ancient folklore of the otherworldly entities that brothers Sam and Dean Winchester face on the hit television show Supernatural—and that have inhabited the shadows of human imagination across countless cultures and centuries.

Following significant advances in deep learning and related areas interest in artificial intelligence (AI) has rapidly grown. In particular, the application of AI in drug discovery provides an opportunity to tackle challenges that previously have been difficult to solve, such as predicting properties, designing molecules and optimising synthetic routes. Artificial Intelligence in Drug Discovery aims to introduce the reader to AI and machine learning tools and techniques, and to outline spe...

In the pursuit of longevity and fulfillment, people have always sought the secret to living a vibrant and fulfilling life, regardless of age. "Ageless Vitality: Embracing the Journey of Healthy Aging" is an enlightening and empowering guide that unveils the keys to aging gracefully and maintaining optimal well-being throughout life's later chapters.In this transformative book, acclaimed wellness expert and gerontologist, Dr. Anna Thompson, draws upon years of research, scientific b...

An otherworldly examination of the unknown that will keep fright fans reading all night. from any strange experience that can't be defined by science to psychic phenomena to monsters and weird creatures, 'The Complete Idiot's Guide® to the Paranormal', focuses on the most interesting and bone-chilling aspects of the Paranormal and the Supernatural, including:- Ghosts and Spirits- Angels, demons and spellcasters- Unexplained phenomena

Throughout the Arab world, Islamist political movements are joining the electoral process. This change alarms some observers and excites other. In recent years, electoral opportunities have opened, and Islamist movements have seized them. But those opportunities, while real, have also been sharply circumscribed. Elections may be freer, but they are not fair. The opposition can run but it generally cannot win. Semiauthoritarian conditions prevail in much of the Arab world, ...

In recent decades, Islamist political movements in many Arab countries have strategically invested in a political process that was stacked heavily against them. And, to the surprise of many, they have actually succeeded by gaining more seats in parliaments and demonstrating their position as the only opposition movements with a popular base. Between Religion and Politics is a broad, cross-national study of Islamist parties in Arab parliamentary elections. The book focuses on those...

Lumbering State, Restless Society offers a comprehensive and compelling understanding of modern Egypt. Nathan J. Brown, Shimaa Hatab, and Amr Adly guide readers through crucial developments in Egyptian politics, society, and economics from the middle of the twentieth century through the present. Integrating diverse perspectives and areas of expertise, including the tools of comparative politics, the book provides an accessible and clear introduction to the Egypt of today alongside...

The Complete Idiot's Guide® to Werewolves takes you deep into the mysterious corners of the werewolf world-and brings you out alive. You'll learn about the history of shapeshifters and werewolves from around the world, savagely entertaining werewolf facts and stories, and how humans transform into these beasts (and what kills them).

"I Forgot!" is a children's book featuring Ralph, the field mouse. It was written to help parents learn additional skills in raising their children. It is the first in a series of books dealing with common themes.This book is intended to be used by parents WITH their children. It's an indirect way to begin to talk about your child's forgetting.The final page of the book is for ADULTS only. The moral of the story andvalues presented in the book are highlighted.Use the final ...

This first systematic treatment of the concept and practice of scaffold hopping shows the tricks of the trade and provides invaluable guidance for the reader's own projects.The first section serves as an introduction to the topic by describing the concept of scaffolds, their discovery, diversity and representation, and their importance for finding new chemical entities. The following part describes the most common tools and methods for scaffold hopping, whether topological, shape-b...

It is clear by now that the label ‘Arab Spring’ has proven too simplistic to describe the uprisings that upended the political order of the Arab world in late 2010. Brutal crackdowns and civil conflict in Syria, Libya, and Yemen dashed the hopes that peaceful democratic revolutions would sweep the region. In other countries, the departure of authoritarian leaders led to many false starts without producing democratic conclusions. Societies that had appeared united in opposition suddenly see...