Integrate RCTs and real-world evidence for stronger regulatory submissionsSince the passage of the 21st Century Cures Act, the landscape of clinical research has transformed dramatically. Today, the integration of real-world data (RWD) and real-world evidence (RWE) with traditional randomized controlled trials (RCTs) is not just innovative - it is essential for modern drug development and regulatory decision-making.This comprehensive volume bridges the meth...

This timely book documents marvelous brachiopod fossils from the Palaeozoic-Mesozoic transition of South China. Numerous beautiful pictures and detailed descriptions (specifically the measurements of body size) of brachiopod species are presented. Systematic discussion on the evolution of brachiopod biodiversity and morphological features across the critical interval is not only extremely important for paleontologists to understand the marine ecosystem evolution from the Palaeozoic to the ...

This book timely provides high-quality records of 32 PTB sections across different depositional settings from terrestrial to marine facies in South China, including descriptions of lithologies, high-resolution correlation of key boundaries and fossil occurrences at each section. This book also analyzes the patterns and processes of the community and ecosystem evolution over space and through time in the lead to the end-Permian mass extinction, and critically analyzes the mostly debated hyp...

This book provides insights into China’s energy consumption and pollution as well as its energy saving policies. It explores energy saving ways and argues for an energy consumption revolution, which includes technologies to improve transportation resource efficiency, modification of existing transportation infrastructure and structure.This book uses various analytical models to study the relationships within the transportation system. It also includes comparative analysis of China,...

Provides a comprehensive overview of the challenges facing agri-food supply chains, including the need to be more sustainable in light of the high environmental costs of global distributionAddresses the external factors that can impact the logistics and performance of supply chains, including political developments, international conflicts and pandemics such as COVID-19Reviews the main agri-food supply chains used in different regions around the world, focussing o...

This book discusses topics related to power electronics, especially electromagnetic transient analysis and control of high-power electronics conversion. It focuses on the re-evaluation of power electronics, transient analysis and modeling, device-based system-safe operating area, and energy balance-based control methods, and presenting, for the first time, numerous experimental results for the transient process of various real-world converters.The book systematically presents both ...

The study of technology and its implications in the medical field has become an increasingly crucial area of research. By integrating technological innovations into clinical practices, patients can receive improved diagnoses and treatments, as well as faster and safer recoveries. Virtual Reality Enhanced Robotic Systems for Disability Rehabilitation is an authoritative reference source for the latest scholarly research on the use of computer-assisted rehabilitation methods for disabled pat...

In a series of disarmingly simple arguments financial market analyst George Cooper challenges the core principles of today's economic orthodoxy and explains how we have created an economy that is inherently unstable and crisis prone. With great skill, he examines the very foundations of today's economic philosophy and adds a compelling analysis of the forces behind economic crisis. His goal is nothing less than preventing the seemingly endless procession of damaging boom-bust cycles, unsus...

This is a strong foundation of human-centric virtual reality design for anyone and everyone involved in creating VR experiences. Without a clear understanding of the human side of virtual reality (VR), the experience will always fail.The VR Book bridges this gap by focusing on human-centered design. Creating compelling VR applications is an incredibly complex challenge. When done well, these experiences can be brilliant and pleasurable, but when done badly...

A unique and important resource, full of critical practical knowledge and technical details made readily accessible.- Tiffany Ito, University of Colorado at Boulder"A comprehensive and engaging guide to EEG methods in social neuroscience; Dickter and Kiefabber offer practical details for conducting EEG research in a social/personality lab, with a broad perspective on how neuroscience can inform psychology. This is a unique and invaluable resource - ...

Most commonly used in economic and public policy decisions, benefit-cost analysis traditionally attempts to calculate a bottom line by assigning monetary values to all factors associated with a proposed project or action. By contrast, multiple account benefit-cost analysis recognizes that all values are complex and that not all consequences can be expressed in monetary terms or incorporated into one summary measure of net benefit.In this textbook, designed for practitioners as well...

In the past two years, the world has experienced how unsound economic practices can disrupt global economic and social order. Today’s volatile global financial situation highlights the importance of managing risk and the consequences of poor decision making.The Doom Loop in the Financial Sector reveals an underlying paradox of risk management: the better we become at assessing risks, the more we feel comfortable taking them. Using the current financial crisis as a case stu...