Extravasation of cytotoxic drugs can lead to serious complications during tumour therapy. This volume is intended as an aid to assess the situation quickly and conclusively should this emergency occur. The substance specific section of the book provides detailed instructions for how to deal with 49 cytotoxic agents so that targeted measures can be started at once. The general section provides comprehensive information on prevention, general measures to be taken in case of extravasation, sp...

Hemostasis and Thrombosis: Practical Guidelines in Clinical ManagementEdited byHussain I Saba MD, PhDProfessor of MedicineDirector of Hematology/Hemophilia/Hemostasis & Thrombosis CenterUSF College of MedicineProfessor EmeritusDepartment of Malignant HematologyMoffitt Cancer Center and Research InstituteTampa, FL, USAHarold R Roberts MDEmeritus Professo...

The first book focusing specifically on frequent and frequently disabling side effects involving the skin, hair and nails in cancer patientsAccording to the World Health Organization, there are approximately thirty million people living with a diagnosis of cancer – the majority of whom will receive surgery, systemic therapy, and/or radiation, and who will suffer from dermatologic adverse events. Dermatologists and oncologists are only beginning to grapple with thes...

As haemophilia is a life-long condition, continuing supervision by a group of medical personnel is required. In many countries this is provided by comprehensive care haemophilia centres where staff of all specialities concerned with treatment- haematologists, paediatricians, nurses, physiotherapists, orthopaedic surgeons - have specialized knowledge.This new book is a definitive resource on the current aspects and issues around haemophilia. Complications of haemophilia care are wel...

Behçet's syndrome can reasonably be considered a unique entity among diseases of the immune system for several reasons: It has specific features and, uniquely among the immune system pathologies, represents a link between autoimmune diseases, systemic vasculitis, and autoinflammatory diseases. In addition, it is of interest to a variety of specialists, including immunologists, rheumatologists, dermatologists, and ophthalmologists, and requires a complex multidisciplinary approach. Many asp...

This book is a timely textbook that covers all aspects of neuroendocrine tumors (NET) from epidemiology, pathological classification and evaluation and molecular biology through to diagnostic imaging methods and therapeutic options, including the latest targeted therapies. The various types of NET are individually discussed, including carcinoid tumors, insulinomas, gastrinomas, glucagonomas, VIPomas, somatostatinomas, PPomas, medullary thyroid carcinomas, adrenocortical cancer, pheochromoc...

In spite of their relatively low prevalence, systemic vasculitides have been the object of intensive basic and clinical investigations over the last few years. As a consequence, important advancements have been achieved: from updated diagnostic and classification criteria and a more rational nomenclature to the recognition of an expanding spectrum of clinical manifestations and potentially devastating complications; from the recognition of the viral etiology of conditions such as HCV-relat...

Primary immunodeficiency diseases (PIDs) are a heterogeneous group of inherited disorders characterized by different defects in the development and function of the immune system. This book aims to increase the clinical awareness and knowledge of practicing clinicians regarding the diagnosis and management of PIDs. In order to achieve this goal, about 90 cases drawn from real life are presented, along with approximately 300 related questions. The selected case reports are the result of the ...

Over the past decade, major advances have occurred in the management of the many fields of cancer treatment encountered by the general surgeon. These developments have evolved from improved understanding of disease biology, high level clinical outcomes studies, as well as translational research with new available therapies. These advances have brought major changes to cancer care and have surfaced new dilemmas in clinical decision-making. Modern cancer management requires an understanding ...

This book offers a complete overview on non colorectal non neuroendocrine (NCRNNE) liver metastases and describes in detail the currently available therapies. Each chapter focuses on the treatment of metastases from a particular primary malignancy and also provides valuable information on incidence, natural history and diagnosis. NCRNNE liver metastases are rare entities compared with colorectal and neuroendocrine metastases, for which the treatments are well codified. While more publicati...

This book is a rich source of information on point-of-care (POC) tests for the diagnosis and treatment of severe hemorrhage, including thromboelastography, thromboelastometry, heparin monitoring systems, and platelet function analyzers (Multiplate, PFA-100, VerifyNow, etc.). The opening chapters focus on the pathophysiology of coagulation and the general characteristics of POC devices. The relevance of POC tests in specific scenarios is then carefully explained, with guidance on their use ...

The purpose of this book, which is written mainly for pharmacothera pists, is to draw the physician's attentions, through specific examples, to iatrogenic (i.e., diagnostically or therapeutically induced) carcino genesis. The book is not intended, however, to arouse public concern. It has been known for some time that each therapeutic measure has a risk-benefit ratio, the estimation of which requires an understanding of carcinogenic side-effects. The number of iatrogenic tumors published s...