Molecules and Medicine provides, for the first time ever, a completely integrated look at chemistry, biology, drug discovery, and medicine. It delves into the discovery, application, and mode of action of more than one hundred of the most significant molecules in use in modern medicine. Opening sections of the book provide a unique, clear, and concise introduction, which enables readers to understand chemical formulas.

Molecules Engineered Against Oncogenic Proteins and CancerA comprehensive review of the latest molecular advances in cancer treatmentFeaturing 91 total small molecule kinase/KRAS inhibitors, 80 of which are FDA-approved, Molecules Engineered Against Oncogenic Proteins and Cancer documents the recent scientific advances that have transformed one of medicine’s most challenging areas—cancer treatment. Most of these inhibitors specific...

Sets forth the history, state of the science, and future directions of drug discoveryEdited by Jie Jack Li and Nobel laureate E. J. Corey, two leading pioneers in drug discovery and medicinal chemistry, this book synthesizes great moments in history, the current state of the science, and future directions of drug discovery into one expertly written and organized work. Exploring all major therapeutic areas, the book introduces readers to all facets and phases of dru...

'Total Synthesis of Natural Products' is written and edited by some of today's leaders in organic chemistry. Eleven chapters cover a range of natural products, from steroids to alkaloids. Each chapter contains an introduction to the natural product in question, descriptions of its biological and pharmacological properties and outlines of total synthesis procedures already carried out. Particular emphasis is placed on novel methodologies developed by the respective authors and their researc...

While Holocaust education is a staple of American schooling, it is rarely studied as a product of the political machine. We often focus on what happens in the classroom, yet the path to those lessons begins years earlier in state legislatures and governors' offices.This essential volume explores the development of Holocaust education in America from the early 1980s to the present. By shifting the focus from pedagogy to politics, this anthology analyzes the rise of two crucial state...

An interdisciplinary excavation of colonoware as a material archive of African, Indigenous, and colonial entanglements across the early American South.In Materializing Colonial Identities in Clay, Jon Bernard Marcoux, Corey A. H. Sattes, and contributors examine colonoware to explore the active roles that African Americans and Indigenous people played in constructing southern colonial culture and part of their shared history with Europeans.

They came in peace …… or so they said. Here are eighteen examples of how they lied. This is an exciting collection of first contact science fiction stories, all completely different! Take a risk—venture into the unknown with us. Who is out there? What will they want from us? Come join us in our adventure to find out how first contact pans out. It will be a great adventure!

Following the success of Flame Tree's Gothic Fantasy collections, this new title gathers together Romantic Fantasy stories inspired by the ecstasy and mystery of Time.Time – at once fleeting and eternal – is a tricksy, intangible dimension. A Breath of Time, part of Flame Tree's exciting new series of Romantic Fantasy titles, is a collection filled with stories of lost loves, love discovered, love unreachable unless Time itself is conquered; stories of tim...

Social Networking and Impression Management: Self-Presentation in the Digital Age, edited by Carolyn Cunningham, offers critical inquiry into how identity is constructed, deconstructed, performed, and perceived on social networking sites (SNSs), such as Facebook, and LinkedIn. The presentation of identity is key to success or failure in the Information Age, especially because SNSs are becoming the dominant form of communication among Internet users. The architecture of SNSs provide opportu...

Television, Social Media, and Fan Culture examines how fans use social media to engage with television programming, characters, and narrative as well as how television uses social media to engage fan cultures. The contributors review the history and impact of social media and television programming; analyze specific programs and the impact of related social media interactions; and scrutinize the past fan culture to anticipate how social media programming will develop in the future. The con...

The Winter 2020-21 Issue. Ploughshares is an award-winning journal of new writing. Since 1971, Ploughshares has discovered and cultivated the freshest voices in contemporary American literature, and now provides readers with thoughtful and entertaining literature in a variety of formats. Find out why the New York Times named Ploughshares “the Triton among minnows.”The Winter 2020-21 Issue, edited by Editor-in-chief Ladette Randolph and Poetry Editor John Skoyles, features poetry an...

This unique collection of chapters takes the reader on a tour to explore innovative preservice and inservice teacher education practices from many regions of the United States, Canada and the world. Each of the chapters offers an authentic, documentary account of successful initiatives that break the traditional mold of teacher education.Section I presents unique preservice teacher preparation programs and initiatives. These chapters offer compelling ideas to readers who seek chang...