The aim of the book is to describe the current approach to meningiomas on the basis of experience gained in the fields of histopathology, biology, radiology and surgery. The first section of the book deals with general diagnostic aspects. The typical histopathological features of meningiomas and the various abnormalities shown by imaging methods are discussed. The second section elucidates the growth pattern of meningiomas arising in various specific locat...

This new edition, like previous ones, offers a precise description of the anatomy of the human hippocampus based upon neurosurgical progress and the wealth of medical imaging methods available. The first part describes the fine structures of the hippocampus and is illustrated with new original figures. A survey is then provided of current concepts explaining the functions of the hippocampus, and the external and internal hippocampal vascularization is precisely described. The last and main...

This book represents the second, fully revised edition of the original volume published in 1982. Experience in neuroradiology has confirmed the outstanding value of computed tomography (CT) for the diagnosis of space-occupying lesions within the skull and orbit. It might be assumed, then, that the second edition of this book would simply represent a numerically expanded continua tion of the popular first edition. That is not the case, however. Advances in imaging techniques have promp ted ...

The classification of brain tumors is up-dated using magnetic resonance spectroscopy technology. The role of cellular immortality in brain tumors is reviewed. Tumor to tumor metastases are a common occurrence; for example, , brain metastasis from breast cancer, lung cancer, and renal cancer is discussed. Genetic profiling and treatment (including neurosurgery) of such brain cancers are explained. Breast cancer patients treated with certain drugs (e.g., capecitabine and lapatinib can develo...

The most recent developments in diagnostic and therapeutic aspects of Gliomas (glioblastoma) in the brain are presented. The importance of personalized medicine and clinical validation for targeted therapy are discussed. The identification of various types of biomarkers (determined by molecular genetics) is included, along with their advantages and limitations as markers in tumor detection and diagnosis. The identification and validation of brain cancer (glioblastoma) genes are discussed. ...

This book systematically describes the angioarchitecture of the spinal cord. Microradiographs of superficial and intrinsic arterial supply and venous drainage patterns provide the anatomical basis needed to understand spinal vascular disorders. These post mortem studies are supplemented by clinical spinal angiographies and case studies.Rapid advances in imaging technology have facilitated the solution of many diagnostic problems concerning diseases of the spine and spinal cord. But...

The most recent developments in diagnostic and therapeutic aspects of Gliomas (Glioblastoma) in the brain are presented. The importance of personalized medicine and clinical validation for targeted therapy are discussed. The identification of various types of biomarkers is included. The identification and validation of brain cancer (glioblastoma) genes are discussed. Role of cancer stem cells in the initiation, progression, and persistence of malignant gliomas is explained. The use of surg...

Various textbooks on stereotactic neurosurgery have been published during the last few years (Riechert 1980, Schaltenbrand and Walker 1982, Spiegel 1982), all of them dealing with functional stereo tactics as the major subject in the field. Diagnostic and therapeutic stereotactic interventions are only briefly described, whereas localization techniques are not yet mentioned. Since 1980, however, an increasing number of reports has been published on CT guided and computer monitored stereota...

Difference between tissue specific stem cells and embryonic stem cells is explained. The advantages of the latter are included. The application of human pluripotent stem cells, mesenchymal stem cells, and hematopoietic stem cells in cancer therapy and tissue/organ regeneration is detailed. Role of neural cancer stem cells in brain tumors, including their role in brain tumor therapy and the role of CD133 stem cell antigen in glioma patients, is emphasized. Therapeutic role of bone marrow-de...