Understand the why behind every clinical sign. Mechanisms of Clinical Signs remains the only text dedicated to explaining the physiological and pathophysiological basis of clinical examination findings.Despite the emergence of technological advancements and artificial intelligence in diagnostic modalities, clinical examination remains essential to the diagnostic and therapeutic process. Rather than describing examination techniques in isolation, this fourth edition reveals the mechanisms t...

A critical examination of translational medicine, when private risk is transferred to the public sector and university research teams become tech startups for global investors.A global shift has secretly transformed science and medicine. Starting in 2003, biomedical research in the West has been reshaped by the emergence of translational science and medicine—the idea that the aim of research is to translate findings as quickly as possible into medical products. In ...

Presented in a useful handbook style, Top 60 Signs for Nurses: Quick reference guide for best practice care outlines the evidence base and clinical value of each clinical sign to assist with interpretation. Each of the signs is related back to the mechanism of action along with clearly documented research to demonstrate the evidence base associated with this sign. - Signs are ordered alphabetically within each chapter outlining a specific body system - Extensive reference lists of up-to-da...

Pathophysiology – what is the cause? Clinical significance – what does it mean? Diagnosis and treatment – what is the predictive value? These are questions that all clinicians should continue to ask themselves from the very beginning of medical training and throughout a lifetime of practice. Organised by body system, Mechanisms of Clinical Signs 3e describes the underlying pathway, differential diagnoses and value of the clinical signs seen during physical examination. - Alphabetical listi...

A robust understanding of the pathophysiological mechanisms behind clinical signs is crucial for medical students and junior doctors. Being able to accurately identify the clinical sequelae of disease during physical examination and connecting cause with consequence is the first step in correct diagnosis and treatment. For example, a patient with rheumatoid arthritis has distinctive hand changes, a patient with Parkinson's disease has a particular tremor, and a patient with liver disease m...

Joseph Roth, whose many novels included The Radetsky March, was one of the most enigmatic writers of the twentieth century. He was a perpetual traveller, a prophet, and a compulsive liar. Dennis Marks makes a journey through the eastern borderlands of Europe to uncover the truth about Roth's lost world.

Opera is all about intense emotion, magical music and overwhelming theatrical spectacle.In this exciting new guide, the many myths that surround opera are exploded, while its transformation from inaccessible high art to affordable, dramatically realistic and easy-to-encounter drama is revealed.The powerful principal players in the opera world - the maestros, superstar divas and directors - are examined in fascinating detail, and questions are asked of opera...

A bestselling title for over 25 years, the updated seventh edition of Talley and O’Connor’s Clinical Examination is an essential read for all student clinicians.Fully updated with the latest clinical data, including specially commissioned research, Clinical Examination addresses the core principles and clinical skills that underpin diagnosis for safe, effective medical practice.Clinical Examination: A systematic guide to physical diagn...

An invaluable self-assessment tool for emergency medicine trainees in Australasia. Emergency Medicine MCQs is an essential resource for Australasia's emergency medicine trainees. A practical self-assessment tool, the book assists trainees as they expand and refine their knowledge of emergency medicine, and will ultimately help them pass the Australasian Emergency Medicine Fellowship examination (FACEM). The multiple-choice questions in Emergency Medicine MCQs cover both the core and non-co...

Although pediatric surgery is a distinct and evolving specialty, it still remains an integral part of most general surgical and paediatric medical practice. Nevertheless, surgery in children does differ from adult practice in various fundamental ways, and there are key physiological and anatomical differences that constantly need underlining. Progress and improvement in outcome has also been rapid but it is sometimes difficult for practitioners to keep themselves up-to-date with the usual ...

Case Studies in Pediatric Critical Care presents a spectrum of real and interesting case studies relating to critically ill children. Each case study includes details of the presenting history and symptomatology, results of investigations and the subsequent critical care management of the patient. Cases have been chosen to illustrate the increasingly diverse range of problems that may be encountered by pediatric critical care physicians throughout the world. Alongside each case is a compre...

Neurocritical Care Board Review: Questions and Answers provides clinicians with a thorough review of the complex subspecialty of Neurocritical Care, using a question-and-answer (Q&A) format. The Q&A format is easily readable, high yield, and serves as good practice for test takers or anyone looking to improve or reinforce essential knowledge. The book covers the key topics pertinent to (and found on) neurocritical care boards, and is organized according to the exam core curriculum...