The discovery of proton pump inhibitors (PPIs) and their development over the years has dramatically changed the management of acid-related diseases. Today, the therapeutic domain of PPIs ranges from relief of symptoms to cure of mucosal lesions in the upper gastrointestinal tract. PPIs are among the most widely sold drugs in the world and are now even available as over-the-counter medication. This publication presents the experience of the last 25 years during which PPIs have become of en...

Digestive-disease-associated mortality accounts for a major part of all deaths in Western societies and inflammatory diseases such as GI infections, viral hepatitis, GERD or cancers due to chronic inflammation have a tangible economic and social impact. What further aggravates the situation is the fact that complex immunological disorders have surfaced where anti-infective treatments are not effective. Fortunately, due to breakthroughs in basic research that are being successfully translat...

The aim of this book is to present a concise yet instructive overview of the most common interventional and therapeutic gastrointestinal endoscopic procedures. Although there exists a large amount of literature dealing with therapeutic endoscopy, this publication stands out for several reasons: To begin with, it has been written by a highly selected group of international experts who contribute their own tried and tested tips and tricks. The various techniques are described in a homogeneou...

The clinical problems and dilemmas which the busy clinician encounters on a daily basis are the main focus of this publication. Emphasizing a clinical rather than a pathophysiological approach to problems, it facilitates access and helps the practicing clinician to develop an effective and efficient diagnostic and therapeutic strategy. Nevertheless, clinically important aspects of pathophysiology are also dealt with in detail when called for. A variety of scenarios that are especially rele...

In recent years, there have been significant advances both in understanding the mechanisms involved in gastrointestinal mucosal injury and protection, as well as in the development of successful strategies for prevention and treatment of gastrointestinal injury. Nevertheless, many people worldwide still suffer from gastrointestinal damage. This book contains contributions by an international panel of researchers in the form of up-to-date reviews on the mechanisms of gastrointestinal injury...

Indocyanine green (ICG) fluorescence has been used for imaging purposes for more than half a century; First employed by ophthalmologists for visualizing the retinal artery in the late 1960s, the application of ICG fluorescence imaging has since been continuously expanded. Recently, advances in imaging technologies have led to renewed attention regarding the use of ICG in the field of hepatobiliary surgery, as a new tool for visualizing the biliary tree and liver tumors. This book introduce...

Sweet dreams! Reading to your child can be great fun and especially so at bedtime when it can be a delightful ritual enjoyed by parents and children alike. These 365 bedtime stories contain enough reading material for an entire year, providing a short, amusing, exciting or surprising story to read aloud at bedtime and help your child fall asleep. From fairy tales, ghost stories, animal adventures to episodes based on childrens' normal, day-to-day activities, there is something to suit ever...

The introduction of anti-tumour necrosis factor (TNF) antibodies into the treatment of patients with IBD about fifteen years ago has dramatically improved the quality of life for patients with severe Crohn's disease and ulcerative colitis. But despite the fact this therapeutic approach has been around for quite some time, there has been no comprehensive overview to date. The book at hand aims to amend this shortcoming, presenting for the first time a thorough overview on TNF action, mechan...

Prize-winning sociologist Lloyd H. Rogler, a founder of cultural psychiatry, gives us an intimately revealing, brilliantly narrated account of fieldwork from San Juan, Puerto Rico to inner-city New Haven. Using his decades of field experience and creative fiction he explores the daily reality of his "informants"—the Barrio Professors—and uncovers the clash between scientific models and local experience over schizophrenia, the political workings of community, and the power of serendipity. R...

A San Francisco Chronicle Best Book of 2004. "A work of scope and profound insight into the divided soul of Mexico."--History TodayThe Life and Times of Mexico is a grand narrative driven by 3,000 years of history: the Indian world, the Spanish invasion, Independence, the 1910 Revolution, the tragic lives of workers in assembly plants along the border, and the experiences of millions of Mexicans who live in the United States. Mexico is seen here as if it ...

The Pulitzer Prize–finalist shares an intimate memoir of grieving his lost wife—and confronting the troubled Mexican city where she grew up.Five years after his wife's untimely death, Francisco Goldman decided to overcome his fear of driving in Mexico City. The widower and award-winning writer wanted to fully embrace his late wife's childhood home and the city that came to mean so much to them. In The Interior Circuit, Goldman chronicles his personal and po...

MANY CULTURES * ONE WORLD"Boricua is what Puerto Ricans call one another as a term of endearment, respect, and cultural affirmation; it is a timeless declaration that transcends gender and color. Boricua is a powerful word that tells the origin and history of the Puerto Rican people."--From the IntroductionFrom the sun-drenched beaches of a beautiful, flamboyan-covered island to the cool, hard pavement of the fierce South Bronx, the remarkable journey of the Puerto Ric...