This book aims to revolutionize information research by introducing a receptive relation understanding of information, which systematically unveils its fundamental characteristics: created ex nihilo, emergence, reciprocity and shareability.Through a thorough exploration of organismic and sensory receptivity, the book establishes a mechanistic foundation for understanding the nature of information. It navigates the origins of biological information and leads readers into a new era o...

This book presents a methodology for the real-time scheduling problems of real-time systems (RTS) from the viewpoint of control theory. Generally, any system can be viewed as an RTS if it performs real-time application functions and behaves correctly depending on given logical activities and satisfying specified deadlines for the activities. This monograph provides broad views and detailed introductions to supervisory control theory (SCT) and its application in real-time scheduling and rec...

This book offers readers an accessible and broad-ranging guide to Environmental Public Interest Litigation (EPIL), which has burgeoned in China over the past decade. The aim of this book is to provide a systematic review of Chinese experiences with EPIL in environmental matters, both with a view to gauging its success to date and well as discussing some more critical aspects. To this end, the book systematically examines the establishment and development of EPIL in China's legal, social, a...

This book represents an ethnographic study of an International Baccalaureate Diploma Program in a school in mainland China, serving Chinese students and staffed by teachers from a variety of origins. It offers in-depth descriptions of the way in which students, teachers, and managers interact and communicate with one another in a variety of school activities. Through the communication process, cultural experiences and understandings are negotiated constantly among school participants. The ...

The book aims to explore the regional innovation capability of China, especially how the frontier regions of China (Guangdong, Jiangsu, Beijing, Shanghai, Zhejiang and Tianjin) transform themselves from an investment-driven economy into an innovation-driven one. With detailed case, data and policy, we analyse the modes of each province and municipality from different perspectives such as comparative advantage in innovation, existing industrial base and culture, the government’s innovation ...

This book integrates a science and business approach to provide an introduction and an insider view of intellectual property issues within the biotech industry, with case studies and examples from developing economy markets. Broad in scope, this book covers key principles in pharmaceutical, industrial, and agricultural biotechnology within four parts. Part 1 details the principles of intellectual property and biotechnology. Part 2 covers plant biotechnology, including biotic and abiotic st...

Glycans play a vital role in modulating protein structure and function from involvement in protein folding, solubility and stability to regulation of tissue distribution, recognition specificity, and biological activity. They can act as both positive and negative regulators of protein function, providing an additional level of control with respect to genetic and environmental conditions.Due to the complexity of glycosylated protein forms, elucidating structural and functional infor...

The existence of ‘cancer stem cells’ (CSCs) has been a topic of heated debate for the last few years within the field of cancer biology. Their continuous characterization in a variety of solid tumors has lead to an abundance of evidence supporting their existence. CSCs are believed to be responsible for resistance against conventional treatment regimes of chemotherapy and radiation, ultimately, leading to metastasis and patient demise. To help aid clinicians, pharmaceutical companies and a...

Gene therapy was conceived during the early and mid part of the 20th century. At first, it was considered a revolutionary biomedical procedure, which could potentially cure any disease for which the molecular bases were understood. Since then, gene therapy has gone through many stages and has evolved from a nearly unrealistic perspective to a real life application. Clinical efficacy in humans was demonstrated at the beginning of this century after its successful application in small-scale ...

Epigenetics is the phenomenon which fine tunes the processes associated with life, beyond that which is specified by the sequence of the genetic material; DNA. The covalent modification of DNA, DNA associated histones, several non histone proteins as well as non coding RNA coherently operate to establish the epigenetic regulation of gene expression in physiological and pathophysiological conditions. This volume presents contributions from worldwide experts presenting their research and fin...

This is the second edition of a very well received book that details how the sumoylation system functions and how it modulates numerous cellular activities. SUMO is a post-translational modifier in the ubiquitin super-family that has gained recognition over the last twenty years as an essential and prevalent regulatory molecule.Individual chapters explore the biochemistry, molecular biology, and cell biology of the sumoylation system and its substrate proteins.The book is d...

Ribonucleases are a ubiquitous and functionally diverse group of enzymes that have a common ability to cleave RNA. Either through scission of internal phosphodiesters, or removal of nucleotides from RNA 5’ or 3’ ends, ribonucleases perform essential roles in gene expression and regulation, genome replication and maintenance, host defense, stress response, and viral strategies of infection. Ribonucleases have also served as highly informative models to understand virtually every aspect of b...