Although some people age faster than others, we cannot turn back time and curb our chronological age. As a research scientist, doctor, and physician-in-chief at Mount Sinai Hospital with four decades of experience, I know that what we can do is change our biological age--the measure of how well our body thrives and its potential for longevity. In The Science of a Long Life, I, Dr. Valentin Fuster, reveal the secret key to longevity. Using the latest research, I guide readers through all as...

Learn how to eat, feel, and live better, prevent avoidable cardiovascular disease, and delay the deterioration that comes with age in this easy-to-read guide.Follow world-renowned cardiologist Valentín Fuster's essential recommendations to a healthier heart and a longer life!Cardiovascular disease affects, and often cuts short, millions of lives every year—and very few doctors have had as much success as Dr. Valentín Fuster in treating this widespread scour...

The landmark text that belongs in the hands of every cardiologist―fully updated and reorganized to make it more patient-centric than everA Doody's Core Title for 2023, 2024 & 2026!World-famous for its authority and clinical relevance, Fuster and Hurst’s The Heart is cardiology’s longest continuously published reference book. Written to meet the ever-changing needs of cardiologists, fellows, and interns, this trusted classi...

Cardiology’s cornerstone text – thoroughly updated to reflect the latest clinical perspectives and cutting-edge topicsHailed for its authority, currency, and ability to translate the latest technical and clinical advances into clinical application, Hurst’s The Heart is the field’s landmark text and cardiology’s longest continuously published reference text. A previous edition of this trusted classic was described by Doody’s as “an outstanding choi...

This issue of Medical Clinics of North America provides the latest essential updates on coronary risk factors. The following key questions are answered. Are new biomarkers informative? LDL: the lower the better? How important is HDL? How much credit does triglyceride deserve? How important is family history of coronary disease? How important is age in determining coronary risk factors? Endothelial progenitor cells, menopause, and coronary risk factors? What is the role of imaging in preven...

Around 250 million people currently suffer from diabetes globally and this number is expected to reach 370 million people within the next 20 years. Fortunately in recent years our understanding of the pathogenesis and management of Type 2 diabetes has increased enormously. Innovative new drugs have been developed and the evidence base for treating diabetes and preventing its complications is now outstanding. This second edition has been fully updated throughout to include all of the latest...

Therapeutic Drug Monitoring: Newer Drugs and Biomarkers features timely topics such as the monitoring of classical and newer drugs, pharmacogenomics and the application of biomarkers in therapeutic drug monitoring. This reference also discusses the limitations of current commercially available immunoassays for therapeutic monitoring. It presents new and sophisticated techniques used for proper determination of blood levels and the clinical utility of therapeutic drug monitoring of contempo...

Chronic overconsumption of sugar and fat elevates plasma levels of insulin and free fatty acids, a process referred to as glucolipotoxicity. This phenomenon may lead to heart failure. This issue explores in depth the relationship between glucolipotoxicity and heart failure.

"Principles of Diabetes Mellitus, Second Edition" is an important update to the comprehensive textbook first published in 2002 and reissued in 2004. It is written for physicians of all specialties who, on a daily basis, deal with an illness which has reached epidemic proportions. The book is also intended for medical students and investigators of all aspects of diabetes.The last five years have witnessed major developments in our understanding of diabetes and in therapeutic approac...

Active Surveillance for Localized Prostate Cancer: A New Paradigm for Clinical Management will serve as a useful resource for physicians dealing with, and interested in, this complex and evolving branch of prostate cancer management. The book will also be of interest to scientifically literate patients and their families. The volume provides an introduction to the concept of active surveillance in oncology in general and prostate cancer specifically. The primary focus is to provide a compr...

The role of free radicals and oxidative stress in neurological disorders has only recently been recognized, leaving clinical neurologists to seek in vain for information on the subject even in major textbooks. What published information there is may consist of brief reminders of the possible association of superoxidase dismutase with familial amyotrophic lateral sclerosis and nitrous oxide with migraine. With luck they may also find information on the purported role of free radicals in the...

This book is a comprehensive resource on psychotropic medications, detailing the latest methods for defining their characteristics, their use in different patient populations, and drug-drug interactions; an important collection of information forclinicians, students, researchers, and members of the pharmaceutical industry alike.The first section provides the foundational principles of these drugs. Mathematical modeling of parameters that affect their entryto,and exit from, the cent...