Aging is associated with morphologic and functional alterations of organ systems including the genitourinary tract. Aging of the bladder leads to urgency, frequency, dysuria, recurrent urinary tract infections and incontinence both in the aging men and women. These symptoms occur frequently, are very distressing and influence daily life of the aging person. Besides patients symptoms, medications and incontinence devices are a tremendous financial burden on health care systems. Understandin...

Surveillance of the fetus is practised by obstetricians and midwives on a daily basis to prevent stillbirth and neonatal death. Yet, there is no specific book to cover this area of practice. Antenatal and Intrapartum Fetal Surveillance fills this gap it covers the knowledge. A comprehensive reference text, the book discusses the use of biochemical and ultrasound markers for screening of genetic, chromosomal and anatomical malformations. It also covers fetal movements, heart rate monitoring...

Neonatal hematology is a fast-growing field, and hematologic problems occur in the majority of sick neonates. Focusing on clinical issues and problem-solving, this is a fully revised and updated revision of a successful practical guide to the pathogenesis, recognition and management of hematologic problems in the neonate. The second edition begins with chapters on the history of neonatal hematology, hematopoiesis, and the immunologic system. Subsequent sections are devoted to erythrocyte d...

The Essential Guide for Clinicians Who Prescribe and Inject BoNTsThis is a detailed and practical guide to botulinum neurotoxin therapy (BoNT) and the wide range of applications for neurological and pain disorders. A unique reference source for new injectors and experienced clinicians alike, this indispensable manual provides information on dose, dilution, and indications for all four FDA-approved toxins in one handy text.Following a brief review o...

Fractures in the Elderly: A Guide to Practical Management provides geriatricians and other medical specialists who provide care for older adults with the vital guidance and most current data and opinions regarding the treatment of elderly patients who sustain a variety of fractures. It also provides orthopedic surgeons with the necessary information and most current data and opinions regarding assessment and management of geriatric conditions that predispose the elderly to fracture, periop...

Treatment of Skin Disease: Comprehensive Therapeutic Strategies has been thoroughly revised to give you the latest treatment options for dermatologic conditions. Mark G. Lebwohl, Warren R. Heymann, John Berth-Jones, and Ian Coulson present an intuitive and easy-to-use, definitive treatment reference that covers the full range of choices for each condition so that you are prepared even when your patients do not respond to primary or secondary therapies. With new chapters on today’s hot topi...

This work covers effectively all aspects of drug-induced pathology that may be encountered within preclinical toxicity studies. It fills a gap in the pathology literature relating to the preclinical safety assessment of new medicines. It systematically describes, in one volume, both spontaneous and drug induced pathology on an organ by organ basis. Information relevant to understanding the nature of pathological changes in pre-clinical studies and assessment of their relevance to the clini...

Primary Sjögren's syndrome is a rheumatic disease affecting around 0.1-0.2% of the adult female population and can result in significant disability without adequate therapy. Diagnosis is often delayed and suggested therapies may not be optimal, and a multidisciplinary approach that includes rheumatologists, ophthalmologists, oral medicine physicians, and others is important to patient management. This volume summarises current understanding of the pathogenesis of the disease, including adv...

Hypertensive disorders are among the most common medical complications of pregnancy, with an incidence of approximately 6-10%. This spectrum of conditions includes essential hypertension, pre-eclampsia and HELLP syndrome. For patients with pre-existing hypertension, management ideally commences prior to conception, and continues through pregnancy to the postnatal period. This book provides information on the evidence-based management of women with hypertension throughout pregnancy, support...

Primary immunodeficiency diseases (PIDs) are a heterogeneous group of inherited disorders characterized by different defects in the development and function of the immune system. This book aims to increase the clinical awareness and knowledge of practicing clinicians regarding the diagnosis and management of PIDs. In order to achieve this goal, about 90 cases drawn from real life are presented, along with approximately 300 related questions. The selected case reports are the result of the ...

This updated and expanded edition developed by the Blood and Marrow Stem Cell Transplant team at Oregon Health & Science University Knight Cancer Institute features the latest medical management guidelines and standards of care for hematopoietic stem cell transplant patients. Spanning the timeline from the initial consultation throughout the transplant process, this handbook includes indications for transplantation and donor selection, treatment guidelines for addressing complications duri...

This book provides the ophthalmologist with the most recently available data on the macular dystrophies, a group of many different inherited or sporadic eye conditions linked by a problem with photoreceptors or other structures of the central retina. Internationally recognized experts in the field present the latest evidence and discuss their own personal experiences with regard to each of the principal dystrophies as well as some very rare entities. Topics covered include molecular biolog...