This book presents basic research on delta operator systems (DOS) with actuator saturation. It proposes null controllable regions of delta operator systems, introduces the enlarging of the domain of attraction and analyzes the performance of DOSs subject to actuator saturation. It also discusses the domain of attraction on different systems in delta domain, and investigates the applications in complicated systems using delta operator approaches.

Nonclinical Evaluation Studies of Cellular and Gene Therapy Products: Strategies, Models, and Regulatory Frameworks systematically explores the nonclinical evaluation of Cell and Gene Therapies (CGT) products, emphasizing risk mitigation and innovation. The book provides comprehensive coverage, including 20+ chapters spanning preclinical toxicology, pharmacokinetics, and novel evaluation models. It is the first book to integrate organ-on-chip models into CGT evaluation, reflecting FDA/NMPA...