Clinical and technical facts about blood group antigens and their antibodies are listed in alphabetical order for ease of finding the information-even in the middle of the night.Contains information about the nearly 300 ISBT recognized blood group antigens and their corresponding antibodies, including:Clinical significance in transfusions and HDNNumber of compatible donors that would be expected to be found in testing 100 donors. Variations in different ethnicities a...

This essential methods manual for immunohematologists (or hematologists and immunohematologists) provides information on genes that encode antigens on red blood cells, platelets and neutrophils. The book begins by covering general concepts in molecular biology and specific protocols such as DNA preparation, PCR-RFLP and allele-specific PCR. Information on the erythrocyte, platelet and neutrophil antigen systems and the molecular basis of polymorphisms are presented clearly in a gene facts ...

Authoritative experts in transfusion medicine describe in critical detail the most important procedures for obtaining, selecting, and transfusing red blood cells to patients. The topics covered include such key issues as transfusion problems in the immunocompromised, the complications of autoantibodies, transfusion of infants with hemolytic disease, difficulties arising from solid organ transplantation, stem cell transfusions, and the challenges of massive transfusion. Also discussed are t...

The Blood Group Antigen FactsBook — winner of a 2013 Highly Commended BMA Medical Book Award for Internal Medicine — has been an essential resource in the hematology, transfusion and immunogenetics fields since its first publication in the late 1990s.The third edition of The Blood Group Antigen FactsBook has been completely revised, updated and expanded to cover all 33 blood group systems. It blends scientific background and clinical applications and provides busy researchers and clinician...

This text is a review of molecular immunohematology (MI). It draws from analyses and case studies around the world and details many techniques used in many labs. It is aimed at anyone interested in how MI is changing blood bank and transfusion medicine.

In this book, we look at the fundamental biology of the human cell from the outside in. While genes and mutations define our cells and how they function, this volume focuses on the biology of the cell rather than on the nuts and bolts of molecular biology. As a result, the book focuses primarily on protein function in normal and diseased states. The volume reveals how cells are constructed and how they are organized so they work effectively. In each case this understanding is related back ...

Building on the success of this book's first edition, Dr. Eric Hansen and Dr. Mack Roach have updated, revised, and expanded the Handbook of Evidence-based Radiation Oncology, a portable reference that utilizes evidence-based medicine as the basis for practical treatment recommendations and guidelines. Organized by body site, concise clinical chapters provide easy access to critical information. Important "pearls" of epidemiology, anatomy, pathology, and clinical presentation are ...

This concise overview of the fundamental concepts of cancer biology is ideal for those with little or no background in the field. A summary of global cancer patterns introduces students to the general principles of how cancers arise and the risk factors involved. By focusing on fundamental examples of the signalling pathways within cells, the functional effects of DNA damage are explained. Later chapters then build on this foundation to provide a comprehensive summary of the major signalli...

Written in a succinct question and answer format, this comprehensive resource covers all areas of nephrology and common clinical scenarios. Nearly 1000 questions with detailed answers provide nephrology fellows, practicing nephrologists and clinicians a better understanding of nephrology and aid preparations for nephrology and internal medicine boards. Absolute Nephrology Review features the latest evidence and guidelines while fulfilling a critical need within the nephrology community.

Based on the most novel approaches and cutting-edge clinical and scientific information regarding radionuclide imaging and therapies for neuroendocrine tumors, this clinical guidebook represents a unique collaborative effort between endocrinologists, nuclear physicians, oncologists, surgeons, physicists, radio-pharmacists and geneticists. It begins with the embryology, classification and molecular genetics of gastroenteropancreatic neuroendocrine tumors and carcinoids, chromaffin cell tumo...

In the summer of 1988, my developmental biology professor announced to the class that hematopoietic stem cells (HSCs) had finally been purified. Somehow, I never forgot the professor’s words. When I started working in Dr. Irv Weissman’s labo- tory at Stanford as a postdoctoral fellow, I realized that the findings mentioned by the professor were from Weissman’s laboratory and had been published in a 1988 edition of the journal Science. It has been over 20 years since the publication of that...

In September 1998 experts from 19 countries came together for an interdisciplinary discussion of the function of animal peroxidases, a family of enzymes embracing myeloperoxidase, eosinophil peroxidase, thyroid peroxidase and lactoperoxidase. Their papers have been updated for publication, yielding a wide-ranging overview of the state of the art. The chapters cover a wide range of topics, including three-dimensional structure of representative family members, their biosynthesis and intrace...