This new edition of Lyme Disease provides up-to-date evidence-based research and covers the significant advances in our understanding of the disorders referred to as Lyme disease or Lyme borreliosis. This book explores the causative organism, its requisite ecosystem, disease epidemiology, host-Borrelia interactions, diagnostic testing, clinical manifestations, therapeutic options, the role of host immunity on pathogenesis and long term prognosis. The authors provide balanced perspectives o...

Lyme disease remains a subject of considerable public and clinical interest, and misunderstandings about Lyme borreliosis continue to cause widespread concern about potential long-term disability. Although the infection occurs primarily in highly endemic areas of Europe and North America, these areas are expanding, as global warming leads to a steady expansion of the tick vectors' habitats. In the period since the 2nd edition was published our understanding of the biology, clinical manifes...