Axial Spondyloarthritis is a timely addition to the Oxford Textbooks in Rheumatology series, providing a comprehensive reference to this rapidly evolving field. The conceptual framework of the disease has now evolved beyond ankylosing spondylitis to encompass a broader concept of axial inflammation. Earlier recognition has opened the door to earlier intervention, and the understanding of the biologic basis of axial SpA has seen significant advances in recent years. The first textb...

Edited by Drs. Juergen Braun and Joachim Sieper, this issue of Rheumatic Disease Clinics comprehensively reviews the state of the art of spondyloarthritis (SpA) diagnosis, prognosis, pathogenesis and genetic insights, and treatment. The worldwide burden of SpA now exceeds that of rheumatoid arthritis. General topics covered include inflammatory back pain, pathophysiology, imaging techniques, and therapeutic strategies.

This thoroughly updated second edition of Fast Facts: Rheumatoid Arthritis provides an easy-to-read overview of how the condition is thought to develop and how it is diagnosed, monitored and treated. Written by two leading UK and US rheumatologists, it covers the many recent developments in this field, including: - Recently published classification criteria - The emerging role of anti-CCP autoantibodies - The latest developments in ultrasound and MRI - The association between RA and cardiovas...

The conditions of Crohn’s disease and ulcerative colitis are excellent examples of how the exponential growth of knowledge in biomedical science can make a remarkable impact on clinical practice and patient’s quality of life. It has led to the development of unique novel immunomodulatory treatments. These are continuously being refined to treat not only the two original conditions in the gut, but the systemic immunologic illness with its associated extraintestinal disorders. New therapies ...

The need for safe and effective use of medicines in children and WHO's initiative "Make Medicines Child Size" have boosted research and educational activities in the area of pediatric clinical drug research. This issue focuses on both general and specific aspects of neonatal and pediatric clinical pharmacology including ethics, pharmacogenomics, metabolomics, adverse drug reactions, pain medication, pulmonary hypertension and several other hot topics. The editors have been able to find out...

To ensure the best possible clinical outcomes for arthritis patients, it is essential that they be seen early and treated appropriately at the earliest opportunity. Early therapy has proven much more effective than that given late. This issue of Rheumatic Disease Clinics of North America brings the rheumatologist up to date on the latest treatments and interventions in evolving arthritis and established early arthritis. Topics covered include early rheumatoid arthritis, psoriatic arthritis...

Educational advancement in the field of psoriatic arthritis which this book will provide is consistent with GRAPPA’s aims and objectives leading to a productive synergy. GRAPPA (Group for Research and Assessment of Psoriasis and Psoriatic Arthritis), is recognized world wide as the leading international society for the study and promotion of awareness of psoriatic arthritis. GRAPPA is an association of leading rheumatologists, dermatologists, representatives of patient service leagues and ...

Sjögren’s Syndrome: Diagnosis and Therapeutics provides a thorough, multisystemic overview of the clinical manifestations of Sjögren’s Syndrome. It contains chapters pertinent across the range of medical specialties that may encounter Sjögren’s Syndrome cases. Chapters are specialty-specific, for easy reference by the relevant medical specialist. In addition to being a diagnostic guide, Sjögren’s Syndrome: Diagnosis and Therapeutics includes a section on prognosis and outcomes of Sjögren’s...

Edited by Drs. Jack Cush and Kathryn Dao, this issue of Rheumatic Disease Clinics of North America addresses one of the most significant issues facing the rheumatologist today––drug safety in a changing world where rheumatoid arthritis (RA) severity is less, patients are being identified and treated at a very early stage, and prevention is on the horizon. Topics covered include: communicating the risk of side effects, urate-lowering therapies, biphosphonates, biologics, malignancy risks, a...

This issue of Medical Clinics of North America provides the latest essential updates on thyroid disorders and diseases. Topics covered include the following: thyroid synthesis and physiology; hyperthyroidism; hypothyroidism; thyroid nodules; goiter; differentiated thyroid cancer; subacute, silent, and postpartum thyroiditis; thyroid and pregnancy; thyroid and the elderly; medications and thyroid hormones; thyroid and the heart; thyroid and lipids; and Graves’ ophthalmology.

This book aims to provide an up-to-date review of the literature in each of the major areas relating to the management of older urological cancer patients, and makes recommendations for best practice and future research. The authors come from a broad geographic spread including the UK, mainland Europe and North America to ensure a worldwide relevance.

As in the first edition of Inflammatory Bowel Diseases this new edition continues to provide readers with a concise, yet in-depth review of many of the important areas in the history, epidemiology, pathogenesis, diagnosis, and treatment of the inflammatory bowel diseases (ulcerative colitis and Crohn's disease), as well as associated issues: extraintestinal manifestations, ostomy care, women's issues, economics, etc. This Second Edition provides the reders with up-to-date, state-of-the art...