This is the fifth edition of a very successful textbook on clinical trials methodology, written by recognized leaders who have long and extensive experience in all areas of clinical trials. The three authors of the first four editions have been joined by two others who add great expertise. A chapter on regulatory issues has been included and the chapter on data monitoring has been split into two and expanded. Many contemporary clinical trial examples have been added. There is much new mate...

Designing Clinical Research sets the standard for providing a practical guide to planning, tabulating, formulating, and implementing clinical research, with an easy-to-read, uncomplicated presentation. This product incorporates current research methodology--including molecular and genetic clinical research--and offers an updated syllabus for conducting a clinical research workshop. Emphasis is on common sense as the main ingredient of good science. The book explains how to choose well-focu...

Evidence-based practice has become a central part of physiotherapy today, but it is still an area which is constantly expanding and being updated. Written by an international team of experts, this second edition continues to outline the basic definitions of evidence-based practice and clinical reasoning, while detailing how to find and critically appraise evidence and clinical practice guidelines and the steps to follow in the implementation and evaluation of evidence. For those struggling...

The Clinical Manual of Psychosomatic Medicine, both educates psychiatrists and mental health professionals practicing in hospital settings about the relationship between physiological processes and psychological and behavioral factors and arms them with the evidence they need to inform hospital administrators about the value of the services they render. Specifically, this new edition: Expands the first edition's content to encompass more than two dozen topics most commonly encountered by...

The third edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory reference it gives clinical investigators in all fields an awareness of the tools required to ensur...

A complete guide to understanding and applying clinical research resultsIdeal for both researchers and healthcare providersUnderstanding Clinical Research addresses both the operational challenges of clinical trials and the needs of clinicians to comprehend the nuances of research methods to accurately analyze study results. This timely resource covers all aspects of clinical trials--from study design and statistics to regulatory oversight--and i...

Meta-analysis, decision analysis, and cost-effectiveness analysis are the cornerstones of evidence-based medicine. These related quantitative methods have become essential tools in the formulation of clinical and public policy based on the synthesis of evidence. All three methods are taught with increasing frequency in medical schools and schools of public health and in health policy courses at the undergraduate and graduate level. This book is a lucid introduction, and will serve the need...

This is a basic book on evidence-based medicine (EBM). It starts with an introduction to the topic. It outlines the relationship between EBM and research and quality of care. Then It goes on to cover the most commonly used modules of EBM, i.e. therapy, diagnosis, prognosis and meta-analysis. Each module starts with an introduction to fundamental concepts, and description of the related research process, and then follows the critical appraisal of related type of research artcle. At the end,...

Originally published by Oxford in 1998, Psycho-Oncology was the first comprehensive text in the field and remains the gold standard today. Edited by a team of leading experts in psycho-oncology, spearheaded by Dr. Jimmie C. Holland, the founder of the field, the text reflects the interdisciplinary nature and global reach of this growing field. Thoroughly updated and developed in collaboration with the American Psychosocial Society and the International Psycho-oncology Society, the third ed...

**Praise for this book:Readable, relevant, and interesting...this book cuts through jargon, recapitulates key concepts, and clarifies with current examples from the literature...recommend[ed].--Doody's Review**Clinical Research for Surgeons is a practical guide for understanding, planning, conducting, and evaluating surgical research. It covers the principles of evidence-based surgery and applies these principles to the design of suitable research studies...

Since publication of the first three editions of this hugely successful book, systematic methods of critical appraisal have been accepted as central to healthcare provision, both in critical applications and in a wider health services and community perspective. This new edition builds on the work of the previous editions by presenting a fully updated and accessible system of critical appraisal applicable to clinical, epidemiological, and public health studies, and related fields. The book ...

Opioids have been used as analgesics for many years, and their use in the management of acute pain related to trauma and surgery is well established. However, patients with persisting pain need a pain management plan that brings relief of symptoms without adverse effects in both the short and longer terms. The prescribing of opioids for chronic non-cancer pain has increased substantially since the first edition of this pocketbook was published, prompting considerable debate regarding the a...