This book describes, extends, and illustrates the metrics of binary classification through worked examples.Worked examples based on pragmatic test accuracy study data are used in chapters to illustrate relevance to day-to-day clinical practice. Readers will gain an understanding of sensitivity and specificity and predictive values along with many other parameters.The contents are highly structured, and the use of worked examples facilitates understanding and interpretation....

This book presents and discusses the numerous measures of test performance that can be derived from 2x2 tables. Worked examples based on pragmatic test accuracy study data are used in chapters to illustrate relevance to day-to-day clinical practice. Readers will gain a good understanding of sensitivity and specificity and predictive values along with many other parameters.The contents are highly structured and the use of worked examples facilitates understanding and interpretation....

This extensively revised second edition provides a comprehensive overview of transient global amnesia (TGA). First, it deals with the history of TGA before moving on to clinical and diagnostic features and differential diagnosis. Subsequent chapters then discuss the investigation and predisposing and precipitating factors for TGA before attempting to synthesise these many strands in order to formulate ideas about the pathogenesis of TGA. Each of the chapters is devoted to a practical and s...

Neurology has always been a discipline in which careful physical examination is paramount. The rich vocabulary of neurology replete with eponyms attests to this historically. The decline in the importance of the examination has long been predicted with the advent of more detailed neuroimaging. However, neuroimaging has often provided a surfeit of information from which salient features have to be identified, dependent upon the neurological examination. A dictionary of neurological signs ha...

This book draws on the author’s experience in conducting pragmatic test accuracy studies on screening instruments for dementia/mild cognitive impairment.To facilitate comprehension and assimilation, all data is presented in an easily accessible, succinct and user-friendly way by means of a structured tabular format that allows tests to be easily compared. The pragmatic design of studies ensures high external validity and generalizability for the test results.The book includ...

This concise, pragmatic, pocket-sized book addresses neurological contributions to the diagnosis and management of dementia through a longitudinal examination of the work undertaken in a dedicated neurological dementia clinic.It covers the use of cognitive and non-cognitive screening instruments and their diagnostic utility and the use of other diagnostic investigations: neuroimaging, neurophysiology and neuropathology. The diagnostic mix is discussed in terms of both neuropsycholo...

This book explains the key steps in planning and executing diagnostic test accuracy studies in dementia, with clear explanations of difficulties and pitfalls and with jargon clearly explained. The emphasis is on pragmatic diagnostic test accuracy studies which can be integrated into day-to-day clinical practice. The book is based on the author’s experience over more than 10 years, which has resulted in the publication of many diagnostic test accuracy studies.The text is structured ...

Dementia in Clinical Practice: A Neurological Perspective addresses neurological contributions to the diagnosis and management of dementia through a longitudinal examination of the work undertaken in dedicated neurological dementia clinics.This concise, pragmatic handbook covers:The use of cognitive screening instruments and their diagnostic utility.The use of non-cognitive (functional, behavioural, neurovegetative) screening instruments and their diagnosti...

This updated and expanded Fourth Edition is an alphabetical listing of commonly presenting neurological signs designed to guide the physician toward the correct clinical diagnosis. The dictionary is focused, problem-based and concise.The structured entries in this practical, clinical resource provide summaries of a wide range of neurological signs. Each entry includes: a definition of the sign; a brief account of the clinical technique required to elicit the sign; a description of ...

Understanding the cognitive aspects of neurological disorders is essential to manage effectively patients suffering from these conditions. This book begins by outlining the various cognitive domains and how these can be tested, before covering in depth the cognitive deficits seen in prototypical neurodegenerative cognitive disorders (Alzheimer's disease, frontotemporal dementias, Huntington's disease, prionoses) and other common neurological disorders that may be complicated by cognitive i...

This expanded, updated third edition summarizes the pragmatic diagnostic accuracy studies of neurological signs and cognitive and non-cognitive screening instruments undertaken in the author’s clinic in the context of day-to-day practice involving patients with cognitive disorders including dementia. A new chapter devoted to comparing and combining instruments is included, and illustrative case studies have been included where relevant.Dementia in Clinical Practice: A Neurologi...

This revised and updated second edition provides a practical and structured overview of some of the most commonly used and easily available cognitive screening instruments applicable in the outpatient clinic and bedside setting. It now includes additional chapters on AD8 and also methodological aspects of systematic cognitive screening instrument assessment from the Cochrane Dementia and Cognitive Improvement Group.Expert authors from around the world equip the reader with clear in...