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Data-driven Modeling for Diabetes

Diagnosis and Treatment

Edición de Vasilis Marmarelis, Georgios Mitsis ...

Series series Engineering (R0)
This contributed volume presents computational models of diabetes that quantify the dynamic interrelationships among key physiological variables implicated in the underlying physiology under a variety of metabolic and behavioral conditions. These variables comprise for example blood glucose concentration and various hormones such as insulin, glucagon, epinephrine, norepinephrine as well as ... Leer más

$1,636 MXN

This contributed volume presents computational models of diabetes that quantify the dynamic interrelationships among key physiological variables implicated in the underlying physiology under a variety of metabolic and behavioral conditions. These variables comprise for example blood glucose concentration and various hormones such as insulin, glucagon, epinephrine, norepinephrine as well as
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ADMET for Medicinal Chemists

A Practical Guide

Edición de Katya Tsaioun, Steven A. Kates ...

This book guides medicinal chemists in how to implement early ADMET testing in their workflow in order to improve both the speed and efficiency of their efforts. Although many pharmaceutical companies have dedicated groups directly interfacing with drug discovery, the scientific principles and strategies are practiced in a variety of different ways. This book answers the need to regularize the ... Leer más

$2,226 MXN

This book guides medicinal chemists in how to implement early ADMET testing in their workflow in order to improve both the speed and efficiency of their efforts. Although many pharmaceutical companies have dedicated groups directly interfacing with drug discovery, the scientific principles and strategies are practiced in a variety of different ways. This book answers the need to regularize the
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Drug-Like Properties

Concepts, Structure Design and Methods from ADME to Toxicity Optimization

de Li Di, Edward H Kerns ...

Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, only a fraction have sufficient ADME (absorption, distribution, metabolism, elimination) properties, and acceptable toxicology properties, to become a drug product that will successfully complete human Phase I clinical trials. Drug-Like Properties: Concepts, Structure Design and ... Leer más

$2,393 MXN

Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, only a fraction have sufficient ADME (absorption, distribution, metabolism, elimination) properties, and acceptable toxicology properties, to become a drug product that will successfully complete human Phase I clinical trials. Drug-Like Properties: Concepts, Structure Design and
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Protein Families

Relating Protein Sequence, Structure, and Function

de Vladimir Uversky ...

Series series Wiley Series in Protein and Peptide Science
New insights into the evolution and nature of proteinsExploring several distinct approaches, this book describes the methods for comparing protein sequences and protein structures in order to identify homologous relationships and classify proteins and protein domains into evolutionary families. Readers will discover the common features as well as the key philosophical differences underlying the ... Leer más

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New insights into the evolution and nature of proteinsExploring several distinct approaches, this book describes the methods for comparing protein sequences and protein structures in order to identify homologous relationships and classify proteins and protein domains into evolutionary families. Readers will discover the common features as well as the key philosophical differences underlying the
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Microarray Technology in Practice

de Steve Russell, Lisa A. Meadows, Roslin R. Russell ...

Using chips composed of thousands of spots, each with the capability of holding DNA molecules corresponding to a given gene, DNA microarray technology has enabled researchers to measure simultaneously gene expression across the genome. As with other large-scale genomics approaches, microarray technologies are broadly applicable across disciplines of life and biomedical sciences, but remain ... Leer más

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Using chips composed of thousands of spots, each with the capability of holding DNA molecules corresponding to a given gene, DNA microarray technology has enabled researchers to measure simultaneously gene expression across the genome. As with other large-scale genomics approaches, microarray technologies are broadly applicable across disciplines of life and biomedical sciences, but remain
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Lipidomics

Technologies and Applications

Edición de Kim Ekroos ...

Focusing on the practical applications, this user-oriented guide presents current technologies and strategies for systems-level lipidanalysis, going beyond basic research to concentrate on commercial uses of lipidomics in biomarker and diagnostic development, as wellas within pharmaceutical drug discovery and development. The editor and authors have experience of the most recent analytical ... Leer más

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Focusing on the practical applications, this user-oriented guide presents current technologies and strategies for systems-level lipidanalysis, going beyond basic research to concentrate on commercial uses of lipidomics in biomarker and diagnostic development, as wellas within pharmaceutical drug discovery and development. The editor and authors have experience of the most recent analytical
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Metabolomics in Practice

Successful Strategies to Generate and Analyze Metabolic Data

Edición de Wolfram Weckwerth, Michael Lämmerhofer ...

Unlike other handbooks in this emerging field, this guide focuses on the challenges and critical parameters in running a metabolomics study, including such often-neglected issues as sample preparation, choice of separation and detection method, recording and evaluating data as well as method validation. By systematically covering the entire workflow, from sample preparation to data processing, the ... Leer más

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Unlike other handbooks in this emerging field, this guide focuses on the challenges and critical parameters in running a metabolomics study, including such often-neglected issues as sample preparation, choice of separation and detection method, recording and evaluating data as well as method validation. By systematically covering the entire workflow, from sample preparation to data processing, the
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Statistical Methods for Evaluating Safety in Medical Product Development

Edición de A. Lawrence Gould ...

Series series Statistics in Practice
This book gives professionals in clinical research valuable information on the challenging issues of the design, execution, and management of clinical trials, and how to resolve these issues effectively. It also provides understanding and practical guidance on the application of contemporary statistical methods to contemporary issues in safety evaluation during medical product development. Each ... Leer más

$1,258 MXN

This book gives professionals in clinical research valuable information on the challenging issues of the design, execution, and management of clinical trials, and how to resolve these issues effectively. It also provides understanding and practical guidance on the application of contemporary statistical methods to contemporary issues in safety evaluation during medical product development. Each
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Computational Modeling Of Gene Regulatory Networks - A Primer

de Hamid Bolouri ...

This book serves as an introduction to the myriad computational approaches to gene regulatory modeling and analysis, and is written specifically with experimental biologists in mind. Mathematical jargon is avoided and explanations are given in intuitive terms. In cases where equations are unavoidable, they are derived from first principles or, at the very least, an intuitive description is ... Leer más

$644 MXN

This book serves as an introduction to the myriad computational approaches to gene regulatory modeling and analysis, and is written specifically with experimental biologists in mind. Mathematical jargon is avoided and explanations are given in intuitive terms. In cases where equations are unavoidable, they are derived from first principles or, at the very least, an intuitive description is
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Prediction Methods for Blood Glucose Concentration

Design, Use and Evaluation

Edición de Eric Renard, John Bagterp Jørgensen, Luigi del Re, Harald Kirchsteiger ...

Series series Engineering (R0)
This book tackles the problem of overshoot and undershoot in blood glucose levels caused by delay in the effects of carbohydrate consumption and insulin administration. The ideas presented here will be very important in maintaining the welfare of insulin-dependent diabetics and avoiding the damaging effects of unpredicted swings in blood glucose – accurate prediction enables the implementation of ... Leer más

$1,636 MXN

This book tackles the problem of overshoot and undershoot in blood glucose levels caused by delay in the effects of carbohydrate consumption and insulin administration. The ideas presented here will be very important in maintaining the welfare of insulin-dependent diabetics and avoiding the damaging effects of unpredicted swings in blood glucose – accurate prediction enables the implementation of
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Computational Biology

Issues and Applications in Oncology

Edición de Tuan Pham ...

Series series Applied Bioinformatics and Biostatistics in Cancer Research
Computational Biology: Issues and Applications in Oncology provides a comprehensive report on recent techniques and results in computational oncology essential to the knowledge of scientists, engineers, as well as postgraduate students working on the areas of computational biology, bioinformatics, and medical informatics.With chapters timely prepared and written by experts in the field, this in ... Leer más

$3,958 MXN

Computational Biology: Issues and Applications in Oncology provides a comprehensive report on recent techniques and results in computational oncology essential to the knowledge of scientists, engineers, as well as postgraduate students working on the areas of computational biology, bioinformatics, and medical informatics.With chapters timely prepared and written by experts in the field, this in
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Computer-Aided Applications in Pharmaceutical Technology

Edición de Jelena Duris ...

Series series Woodhead Publishing Series in Biomedicine
Research and development in the pharmaceutical industry is a time-consuming and expensive process, making it difficult for newly developed drugs to be formulated into commercially available products. Both formulation and process development can be optimized by means of statistically organized experiments, artificial intelligence and other computational methods. Simultaneous development and ... Leer más

$2,572 MXN

Research and development in the pharmaceutical industry is a time-consuming and expensive process, making it difficult for newly developed drugs to be formulated into commercially available products. Both formulation and process development can be optimized by means of statistically organized experiments, artificial intelligence and other computational methods. Simultaneous development and
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ADMET for Medicinal Chemists

Drug-Like Properties

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Microarray Technology in Practice

Lipidomics

Metabolomics in Practice

Statistical Methods for Evaluating Safety in Medical Product Development

Computational Modeling Of Gene Regulatory Networks - A Primer

Prediction Methods for Blood Glucose Concentration

Computational Biology

Computer-Aided Applications in Pharmaceutical Technology