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  • Transport Mediated by Electrified Interfaces

    Studies in the Linear, Non-linear and far from Equilibrium Regimes

    Collection Livre 18 - Studies in Interface Science
    Transport Mediated by Electrified Interfaces provides an overview of the innovative use of electro-kinetic phenomena in experimentally exploring non-equilibrium regions of chemically non-reacting systems. Transport phenomena mediated by charged liquid-liquid interfaces and solid-liquid interfaces are also covered. Transport phenomena mediated by electrified interfaces are discussed in the context ... En savoir plus

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  • Surface Activity in Drug Action

    Collection Livre 21 - Studies in Interface Science
    Surface activity is present in living systems; for example in body fluid or cell soup and molecules of surface-active nature are crucial to living matter and its organization. Surface Activity in Drug Action proposes "a liquid membrane hypothesis of drug action" for surface-active drugs. Chapters 1-7 contains an account of the hypothesis and chapter 8 contains a general account of the application ... En savoir plus

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    Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, only a fraction have sufficient ADME (absorption, distribution, metabolism, elimination) properties, and acceptable toxicology properties, to become a drug product that will successfully complete human Phase I clinical trials. Drug-Like Properties: Concepts, Structure Design and ... En savoir plus

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  • Monoclonal Antibody and Peptide-Targeted Radiotherapy of Cancer

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    Oncology Book of 2011, British Medical Association's Medical Book AwardsAwarded first prize in the Oncology category at the 2011 BMA Medical Book Awards, Monoclonal Antibody and Peptide-Targeted Radiotherapy of Cancer helps readers understand this hot pharmaceutical field with up-to-date developments. Expert discussion covers a range of diverse topics associated with this field, including the ... En savoir plus

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  • Natural Products in Medicinal Chemistry

    Collection Livre 60 - Methods & Principles in Medicinal Chemistry
    The inspiration provided by biologically active natural products to conceive of hybrids, congeners, analogs and unnatural variants is discussed by experts in the field in 16 highly informative chapters.Using well-documented studies over the past decade, this timely monograph demonstrates the current importance and future potential of natural products as starting points for the development of new ... En savoir plus

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  • Pharmacology

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    Pharmacology meets the rapidly emerging needs of programs training pharmacologic scientists seeking careers in basic research and drug discovery rather than such applied fields as pharmacy and medicine. While the market is crowded with many clinical and therapeutic pharmacology textbooks, the field of pharmacology is booming with the prospects of discovering new drugs, and virtually no extant ... En savoir plus

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  • Drug Delivery in Oncology

    From Basic Research to Cancer Therapy

    In this first authoritative overview on modern cancer chemotherapy 121 international specialists have contributed their experience and recent data for what is likely to become the gold standard in the field.The authors summarize knowledge gained over the past decade, from basic concepts to successful applications in the clinic, covering active and passive targeting strategies as well as tissue ... En savoir plus

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  • Bioinorganic Medicinal Chemistry

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    This book gives a comprehensive overview about medicinal inorganic chemistry. Topics like targeting strategies, mechanism of action, Pt-based antitumor drugs, radiopharmaceuticals are covered in detail and offer the reader an in-depth overview about this important topic. ... En savoir plus

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  • Aggregation of Therapeutic Proteins

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    This book gives pharmaceutical scientists an up-to-date resource on protein aggregation and its consequences, and available methods to control or slow down the aggregation process. While significant progress has been made in the past decade, the current understanding of protein aggregation and its consequences is still immature. Prevention or even moderate inhibition of protein aggregation has ... En savoir plus

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  • Lipidomics

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  • Antibody-Mediated Drug Delivery Systems

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    This book covers various aspects of antibody mediated drug delivery systems – theoretical aspects, processing, viral and non-viral vectors, and fields where these systems find and /or are being evaluated for applications as therapeutics and diagnostic treatment. Chapters discuss actual applications of techniques used for formulation and characterization. Applications areas include cancer, ... En savoir plus

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  • A Practical Guide to Protein and Peptide Purification for Microsequencing

    Modifié par Paul T. Matsudaira ...
    Why a Second Edition?The Second Edition provides practical answers to the general question, "How can I obtain useful sequence information from my protein or peptide?" rather than the more specific question asked in the first edition, "How can I obtain the N-terminal sequence?" Important new methods include ways of dealing with blocked N termini, computer analysis of protein sequences, and the ... En savoir plus

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