Progress in science is often promoted by a new method. Diagnostic cytology, however, developed slowly over a whole century, mainly in differentiating malignant from benign cells from various tissues. The decisive step in this development was the intensive investigation of one local ization by Papanicolaou: The application of cytology for screening in the field of gynecologic oncology made it an acknowledged technique. Consequently, materials inves tigated before were tested again on a larg...

This book is an introduction to quality initiative for vascular surgery and medicine. It will help to introduce the best available treatment options into clinical practice. For the 21 major vascular surgical diseases, this book enables targeted evidence-based treatment choice. Basics are the most recent published treatment results of open surgery and endovascular procedures.- What do international guidelines recommend?- Which treatment results have been published in recent ...

This book is an introduction to quality initiative for vascular surgery and medicine. Originally published in German, the book is written by leading experts who utilise their professional expertise and insight to help raise the level of patient safety, quality of care, and training of junior vascular physicians.This books aims to bring together the best available current treatment and information, including recent guidelines, meta-analyses, and randomised trials to help put evidenc...

Concepts on the Causal Genesis of Human Intestinal Tumors The action of chemical substances has a significant role in the genesis of human tumors. It is assumed that most human tumors are induced by exogenous chemical noxae (Schmahl, 1970;Heidelberger, 1975; and others). In the course of intensive efforts to discover the principles of tumor etiology, important insights have resulted in recent years. These are that chemical carcinogens do not only arise as products of our tech nologic...

This second volume reports on the reaction patterns of lymph nodes in neoplastic and immunodeficient diseases. Based on the contents of volume 1, it presents a detailed survey of lymph node structures and their cellular components under these conditions. The patterns of nodal reactions to the development and spread of cancer have recently been investigated and discussed by several authors. Here, the immediate interactions between tumor tissue and the regional nodes have been assessed in ex...

It is a great pleasure and honor to be asked to participate in the translation of this important and historical volume on thoracic surgery and to provide this foreword. Martin Kirschner of Mannheim/Heidelberg was an early pioneer in thoracic and esophageal surgery. His operation for bypass of the esophagus using the entire stomach remains a standard of the surgical armamentarium to this date. The original Kirschner Textbook of Surgery was a standard in its day. We are fortunate that Profes...

During the past few years, a considerable number of monographs on bone tumors have been published. They are mainly restricted to bone tumors as clinical-pathological entities, since their diagnosis, more than that of other tumors, requires the interdisciplinary cooperation between orthopedic specialist, radiologist, and pathologist. However, investiga tions concerning the histogenesis of bone tumors are rather limited, although they might be helpful in explaining the unique morphological h...