Globalization has transformed our world, but not our political systems. Understanding the world of human development can help us avoid the narcissism that threatens whole societies with despotism. Understanding U.S. secrecy and militarism can help us avoid the failure of our imperial state. Vigorously addressing U.S. and global economic inequality grants our world the chance for free governance.By the same author as the novel On Fire by Thomas Anderson, also available on Smashwords...

Among the stories of world-wide renown, not the least stirring are those that have gathered about the names of national heroes. The Æneid, the Nibelungenlied, the Chanson de Roland, the Morte D'Arthur,—they are not history, but they have been as National Anthems to the races, and their magic is not yet dead, is how Beatrice Clay unravels the magical journey through the most interesting adventures of King Arthur, his heirs and his companions.

In the depths of grief, Elizabeth Barrett Browning's Consolation offers a beacon of solace and hope. Written after the loss of her beloved brother, this collection of poems explores the raw emotions of bereavement, the search for meaning in the face of tragedy, and the transformative power of love and memory. Through lyrical verses and poignant reflections, Browning's words provide a gentle embrace, reminding us that even in the darkest of times, there is always a glimmer of light to guide...

In this text, the small team of expert authors presents the field in a comprehensive and accessible manner that is well suited for students and junior researchers.The result is a highly readable and systematically structured introduction to antimicrobial peptides, their structure, biological function and mode of action. The authors point the way towards a rational design of this potentially highly effective new class of clinical antibiotics on the brink of industrial application. T...

New advances in proteomics, driven largely by developments in mass spectrometry, continue to reveal the complexity and diversity of pathogenic mechanisms among microbes that underpin infectious diseases. Therefore a new era in medical microbiology is demanding a rapid transition from current procedures to high throughput analytical systems for the diagnosis of microbial pathogens.This book covers the broad microbiological applications of proteomics and mass spectrometry. It is divi...

Oncology Book of 2011, British Medical Association's Medical Book AwardsAwarded first prize in the Oncology category at the 2011 BMA Medical Book Awards, Monoclonal Antibody and Peptide-Targeted Radiotherapy of Cancer helps readers understand this hot pharmaceutical field with up-to-date developments. Expert discussion covers a range of diverse topics associated with this field, including the optimization of design of biomolecules and radiochemistry, cell ...

The purpose of the book is to introduce platelets, and their functional role in thrombotic and cardiovascular disease, justifying the relevance of platelet proteomics research. Focus then shifts to the recent developments on mass spectrometry (MS)-based proteomics. This chapter shows potential applications for platelet proteomics not yet carried out. It includes examples of post-translational modifications (PTMs) analysis in platelets.The second part of the book focuses on the main...

Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditio...

Zebrafish: Methods for Assessing Drug Safety and Toxicity offers a practical guide for using zebrafish as a tool for toxicology studies.Consolidating key protocols and approaches to help researchers navigate the important and evolving field of zebrafish models for toxicity screening, this new title describes the methods for using the zebrafish as a model organism to assess compound-induced toxicity on all major organs. Individual chapters that concentrate on assays for eac...

The inspiration provided by biologically active natural products to conceive of hybrids, congeners, analogs and unnatural variants is discussed by experts in the field in 16 highly informative chapters.Using well-documented studies over the past decade, this timely monograph demonstrates the current importance and future potential of natural products as starting points for the development of new drugs with improved properties over their progenitors.The examples are chosen s...

An increasingly aging population will add to the number of individuals suffering from amyloid. Protein Misfolding Diseases provides a systematic overview of the current and emerging therapies for these types of protein misfolding diseases, including Alzheimer's, Parkinson's, and Mad Cow. The book emphasizes therapeutics in an amyloid disease context to help students, faculty, scientific researchers, and doctors working with protein misfolding diseases bridge the gap between basic ...

This book provides comprehensive up-to-date information on the structure and function of immunoglobulins. It describes the basic features of these molecules, which assists the reader in understanding how they function as an integral part of the immune system. The Immunoglobulins describes the localization and structure of different binding sites of immunoglobulin molecules, including the antigen-binding site, on the basis of latest x-ray crystallography studies. It discusses recently devel...