This book systematically introduces the new technology used in the construction of underwater large slurry shields under complex conditions. The basic principles, scope of application, construction technology and technical points of the key technologies such as the origin and arrival of the shield, crossing the shallow soil in the middle of the river, crossing the guard, and changing the knife and opening the knife are clarified.

Metabolic engineering has been developed over the past 20 years to become an important tool for the rational engineering of industrial microorganisms. This book has a particular interest in the methods and applications of metabolic engineering to improve the production and yield of a variety of different metabolites. The overall goal is to achieve a better understanding of the metabolism in different microorganisms, and provide a rational basis to reprogram microorganisms for improved bioc...

Carbon Dioxide Reduction through Advanced Conversion and Utilization Technologies covers fundamentals, advanced conversion technologies, economic feasibility analysis, and future research directions in the field of CO2 conversion and utilization.This book emphasizes principles of various conversion technologies for CO2 reduction such as enzymatic conversion, mineralization, thermochemical, photochemical, and electrochemical processes. It addresses material...

This book provides readers with sufficient insight into battery equalization control technologies from both theoretical and engineering perspectives. Distinguished from most of the existing works that focus on the hardware design of active equalizers, this book intends to comprehensively introduce equalization control strategies for lithium-ion battery packs. The validity and reliability of the control strategies in this book have been verified by theory and experiments.This book s...

The blood-brain-barrier serves to encapsulate and protect the central nervous system, but it also presents a major barricade to therapeutic drug delivery. Poor penetration is the most common hurdle to translating a promising experimental therapy that uses invasive delivery methods to a clinically useful application. In the last 10 years, intranasal delivery of various therapeutic compounds including small chemicals, large proteins, and even stem cells has proven to be very effective in byp...

This book provides up-to-date developments in the stability analysis and (anti-)synchronization control area for complex-valued neural networks systems with time delay. It brings out the characteristic systematism in them and points out further insight to solve relevant problems. It presents a comprehensive, up-to-date, and detailed treatment of dynamical behaviors including stability analysis and (anti-)synchronization control. The materials included in the book are mainly based on the re...

This book introduces a pioneering framework for monitoring and controlling autonomous energy systems, distinguished by its use of physics-informed deep neural networks. These networks provide accurate estimations and forecasts, interlacing with advanced composite optimization algorithms to simplify the complex processes of state estimation. This approach not only boosts operational efficiency but also maximizes flexibility through a data-driven methodology integrated with physics-based pri...

Finally, a stand-alone, all-inclusive textbook on yeast biology.Based on the feedback resulting from his highly successful monograph, Horst Feldmann has totally rewritten he contents to produce a comprehensive, student-friendly textbook on the topic. The scope has been widened, with almost double the content so as to include all aspects of yeast biology, from genetics via cell biology right up to biotechnology applications. The cell and molecular biology sections have been vastly ex...

This book was written for graduate and medical students, as well as clinicians and postdoctoral researchers. It describes the theory of alternative pre-mRNA splicing intwelve introductory chapters and then introduces protocols and their theoretical background relevant for experimental research. These 43 practical chapters cover: Basic methods, Detection of splicing events, Analysis of alternative pre-mRNA splicing in vitro and in vivo, Manipulation of splicing events, and Bioinforma...

"This volume inspires. It certainly will be much appreciated by cell biologists all over the world."Quarterly Review of Biology, March 2009This book is the eagerly awaited second edition of the best-selling Mitochondria, a book widely acknowledged as the first modern, truly comprehensive authored work on the important, scientifically fundamental topic of the cellular organelles known as mitochondria.This new edition brings readers c...

Every time a cell divides, a copy of its genomic DNA has to be faithfully copied to generate new genomic DNA for the daughter cells. The process of DNA replication needs to be precisely regulated to ensure that replication of the genome is complete and accurate, but that re-replication does not occur. Errors in DNA replication can lead to genome instability and cancer. The process of replication initiation is of paramount importance, because once the cell is committed to replicate DNA, it ...

This book describes recent progress in enzyme-driven green syntheses of industrially important molecules. The first three introductory chapters overview recent technological advances in enzymes and cell-based transformations, and green chemistry metrics for synthetic efficiency. The remaining chapters are directed to case studies in biotechnological production of pharmaceuticals (small molecules, natural products and biologics), flavors, fragrance and cosmetics, fine chemicals, value-added...