A variety of new cancer therapy modalities are discussed and evaluated in this book. It aims to demonstrate that the combination of classical chemo- and radiotherapy with new approaches in the field of immunotherapy can result in an improved treatment modality. Immunotherapy in this context consists of therapy with monoclonal antibodies, hematopoietic growth factors and other lymphokines. Results of early clinical trials with IL-2, GM-CSF and monoclonal antibodies against gastrointestinal ...

In anaesthetist Dr Kevin Fong's television programmes he has often demonstrated the impact of extremes on the human body by using his own body as a 'guinea pig'. So Dr Fong is well placed to share his experience of the sheer audacity of medical practice at extreme physiological limits, where human life is balanced on a knife edge. Through gripping accounts of extraordinary events and pioneering medicine, Dr Fong explores how our body responds when tested by the extremes of heat and cold, v...

Specifically designed to help candidates revise for the MRCS exam, this book features 350 Single Best Answer multiple choice questions, covering the whole syllabus. Containing everything candidates need to pass the MRCS Part A SBA section of the exam, it focuses intensively on the application of basic sciences (applied surgical anatomy, physiology, and pathology) to the management of surgical patients. The high level of detail included within the questions and their explanations allows eff...

Landmark Papers in General Surgery will give surgeons, surgical trainees and other healthcare professionals an expert appraisal of key papers, and fast access to the evidence base behind current clinical practice in General Surgery. Each chapter draws together a fascinating selection of the most important clinical trials across every subspecialty within General Surgery, as selected and appraised by a panel of experts. Organized according to a common format, each discussion offers ...

This comprehensive review of vascular disease in the vertebrobasilar circulation is based on Dr Louis R. Caplan's extensive experience and observation of patients from the New England Medical Center posterior circulation stroke registry. It benefits from an organized, uniform, and coherent analysis of all types of vascular disease involving the posterior circulation, presented by a single author who is one of the world's leading authorities on this topic. This new edition is fully updated ...

Both editors are active duty officers and surgeons in the U.S. Army. Dr. Martin is a fellowship trained trauma surgeon who is currently the Trauma Medical Director at Madigan Army Medical Center. He has served as the Chief of Surgery with the 47th Combat Support Hospital (CSH) in Tikrit, Iraq in 2005 to 2006, and most recently as the Chief of Trauma and General Surgery with the 28th CSH in Baghdad, Iraq in 2007 to 2008. He has published multiple peer-reviewed journal articles and surgical ...

Introducing this monograph by expressing our heartfeIt thanks to all those who have contributed to its success may seem no more than a rhetorical exercise. However, at the same time we feel duty bound to add our sincere apologies, for we know that many of the dis tinguished authors of the various chapters have been hard put to find any relevant information in the existing literature. The plain fact is that very little has been said and written about pancreatic fistulas compared with other ...

This book is dedicated to the memory of Walter Brendel, late Professor of Experimental Surgery and Chairman of the Institute for Surgical Research at the University of Munich, Germany. For 20 years Walter Brendel organized the renowned Round Table Symposium on Applied Immunology, first in Kitzbiihel and later in Axams, Austria. On the occasion of the 20th symposium in January 1989 he gathered together a number of scientists who have been leaders in the field of transplantation immunology a...

The management of ankle injuries has long been a stumbling block for orthopae dists in training. As a first year resident, I was fortunate to encounter the series of articles by N. Lauge-Hansen and T. Baek Kristensen that classified ankle injuries according to their mechanism. I found this information quite helpful throughout my residency and early years of practice. Several years ago, an attempt was made to summarize this material for the benefit of the orthopaedic house staff of Thomas J...

Because the base of the skull has proven to be one of the most challenging regions of the body to access, treatment options were once limited for patients with tumors or lesions in this area. However, with recent advancements and breakthroughs in treatment, patients with skull base tumors now have an array of surgical options that can help them return to leading a normal and active life. The Endoscopic Endonasal Approach (EEA) is an innovative surgical technique used to remove brain tumors...

Bariatric and Metabolic Surgery is recognized to be an important and effective option for the treatment of severe obesity and the various associated conditions and diseases. This book presents state of the art knowledge on such surgery with the aim of facilitating the sharing and exchange of knowledge, documenting effective techniques, and enhancing safety and outcomes. All technical aspects are covered in detail, and the text is complemented by many helpful illustrations. A further key fe...

In conventional partial resection of parenchymatous organs significant bleeding is one of the main problems, especially in neonates and infants. The patients rapidly lose considerable amounts of their small blood volume. Laser light leads to photo thermal effects in tissue and causes coagulation, drying up, carbonization and evaporization, depending on the temperature. The neodymium Y AG laser emits nonvisible light in the near infrared with a wavelength of l. 0611m. This wavelength implie...