Wolf's discovery demonstrating that a reporter gene is expressed in myocytes subsequent to injection of naked DNA, was exploited by immunologists and vaccinologists to develop a new generation of vaccines. This observation galvanized the research and in a short lapse of time, an oceanic volume of knowledge has been accumulated. The research carried out in a variety of animal models showed the efficacy of genetic immunization against viruses, bacteria, and some parasites by the ability to i...

Recent advances in immunology and biology have opened new horizons in cancer therapy, included in the expanding array of cancer treatment options, which are immunotherapies, or cancer vaccines, for both solid and blood borne cancers. Cancer Vaccines: From Research to Clinical Practice is the first text in the field to bring immunotherapy treatments from the laboratory trial to the bedside for the practicing oncologist.Cancer Vaccines: From Research to Clini...

Cellular and Molecular Immunology takes a comprehensive yet straightforward approach to the latest developments in this active and fast-changing field. Drs. Abul K. Abbas, Andrew H. Lichtman, and Shiv Pillai present sweeping updates in this new edition to cover antigen receptors and signal transduction in immune cells, mucosal and skin immunity, cytokines, leukocyte-endothelial interaction, and more. This reference is the up-to-date and readable textbook you need to master the complex subj...

'An excellent book, the most objective short account I know of all the various approaches to depression.' Anthony StorrSeveral years ago, Lewis Wolpert had a severe episode of depression. Despite a happy marriage and successful scientific career, he could think only of suicide. When he did recover, he became aware of the stigma attached to depression - and just how difficult it was to get reliable information. With characteristic candour and determination he set about writ...

The prospect of parenthood represents a milestone in anyones life course and is often a period of stress and challenge. There are a number of significant mental health problems that can occur during the perinatal period, the consequences of which can be both enduring and, occasionally, life threatening. However, irrespective of the specifics of the clinical manifestation of a disturbance, the distress and misery that accompanies it has significant ramifications for the mother or mother-to-be ...

This fourth edition of the best-selling textbook, Human Genetics and Genomics, clearly explains the key principles needed by medical and health sciences students, from the basis of molecular genetics, to clinical applications used in the treatment of both rare and common conditions.A newly expanded Part 1, Basic Principles of Human Genetics, focuses on introducing the reader to key concepts such as Mendelian principles, DNA replication and gene expression. Part 2, Genetics...

Tough Test Questions? Missed Lectures? Not Enough Time?Fortunately for you, there's Schaum's Outlines. More than 40 million students have trusted Schaum's to help them succeed in the classroom and on exams. Schaum's is the key to faster learning and higher grades in every subject. Each Outline presents all the essential course information in an easy-to-follow, topic-by-topic format. You also get hundreds of examples, solved problems, and practice exercises to test ...

The biological and psychological basis of pet therapy / animal-assisted therapy and what this means for practice "A comprehensive, scientific foundation for human-animal therapy." (Judith Solomon) In recent years, the ancient symbiosis between humans and their pets has entered a new phase, marked by the burgeoning clinical specialty of human-animal therapy. This approach uses the relationship between humans and their (mainly) mammalian pets to support the growth of emotion regulation, soci...

Help your patients through the maze of infertility treatmentsInfertility is suffered by around 1 in 7 couples and can be a source of confusion for both partners, providing high stress on relationships. 25% of cases are explained through male infertility, 50% through female infertility, whilst 25% are generally unexplained. The possible causes and solutions are many and complex.Infertility, one of the first in the new Gynecology in Practice series, assists g...

We remember the admonition of our mothers: “Treat others as you want them to treat you.” But what if being nice was something we were inclined by nature to do anyway? Renowned neuroscientist Donald Pfaff upends our entire understanding of ethics and social contracts with an intriguing proposition: the Golden Rule is hardwired into the human brain.Pfaff, the researcher who first discovered the connections between specific brain circuits and certain behaviors, contends that the basic...

Babies who cry a lot, or are unsettled in the night, are common sources of concern for parents and, consequently, costly problems for health services. In this book, Ian St James-Roberts summarises the evidence concerning infant crying and sleeping problems to provide a new evidence-based approach to these common challenges for parents and health services. The book begins by distinguishing between infant and parental parts of the problems and provides guidelines for assessing each issue.