This book addresses Epigenetics in Cancer and covers the most recent advances in RNA/histone/DNA epigenetics in Oncology. RNA/histone/DNA epigenetics have been shown to play pivotal roles in cancer initiation, progression, maintenance and drug response/resistance, tumor microenvironment, cancer stem cell self-renewal, cancer metabolism, and tumor immune evasion. In particular, research in RNA cancer epigenetics has made impressive progress in the last few years.Individual chapters ...

The five movie scripts in Three Generations of Women Under Half the Sky higlight life in modern China, exploring topics such as gender disparity, marriage, loyalty, cultural conflicts, and more. In the title script, Grandma plans to swap her granddaughter for a boy in the delivery room. Later, the granddaughter returns home from Australia with degrees in gender equality and gives birth for a powerful military family. In “Faith, Marriage and Loyalty,” George, a college student, loses his bi...

The thoroughly updated and expanded Second Edition of Greg G. Chen, Lynne A. Weikart, and Daniel W. Williams’ Budget Tools: Financial Methods in the Public Sector brings together scores of exercises that will take students through the process of public budgeting, from organizing data through analysis and presentation. This thoroughly revised text has been restructured – it now has 30 compact modules to focus on individual skills a...

In the nonprofit sector, money drives mission. Well-managed budgets and investments can spur long-term growth and achievement, while financial mismanagement can damage and even destroy organizations. Weikart, Chen, and Sermier—in their exciting new text geared wholly to nonprofits—provide the financial tools nonprofit managers need to thrive in pursuit of mission success.Given the wide array of nonprofit managers′ backgrounds, and recognizing that there is often an inherent fear of...

Life in twentieth-century Communist China is not easy for its people who must navigate through hardships, oppression, and many other complex challenges. Within five original screenplays, Greg Gang CHEN shares insights into the lives of diverse characters demonstrating the resilience of the human spirit, despite the obstacles standing in the way: After intellectuals settle in a village in the late sixties, a school is established in a Buddhist temple. As locals and new arrivals recite Chair...

Generative Machine Learning Models in Medical Image Computing" provides a comprehensive exploration of generative modeling techniques tailored to the unique demands of medical imaging. This book presents an in-depth overview of cutting-edge generative models such as GANs, VAEs, and diffusion models, examining how they enable groundbreaking applications in medical image synthesis, reconstruction, and enhancement. Covering diverse imaging modalities like MRI, CT, and ultrasound, it illustrat...

The growth of what some academics refer to as 'the policy analysis movement' represents an effort to reform certain aspects of government behaviour. The policy analysis movement is the result of efforts made by actors inside and outside formal political decision-making processes to improve policy outcomes by applying systematic evaluative rationality to the development and implementation of policy options. This volume offers a comprehensive overview of the many ways in which the policy ana...

The blame game, with its finger-pointing and mutual buck-passing, is a familiar feature of politics and organizational life, and blame avoidance pervades government and public organizations at every level. Political and bureaucratic blame games and blame avoidance are more often condemned than analyzed. In The Blame Game, Christopher Hood takes a different approach by showing how blame avoidance shapes the workings of government and public services. Arguing that the blaming phenom...

In light of an increasingly tumultuous political landscape, the success, efficiency, and performance of government employees and departments is more critical than ever before. With over thirty years of experience working for the federal government, author Stewart Liff shares firsthand knowledge about the key to improving a government team’s performance results: understanding how different management systems perform individually and interact with one another. Improving the Performance of Go...

Based on exclusive interviews, the inside story of how America's emergency response system failed and how it remains dangerously brokenWhen Hurricane Katrina roared ashore on the morning of August 29, 2005, federal and state officials were not prepared for the devastation it would bring—despite all the drills, exercises, and warnings. In this troubling exposé of what went wrong, Christopher Cooper and Robert Block of The Wall Street Journal show that the fl...

The State as Cultural Practice offers a fully worked out account of the authors' distinctive interpretive approach to political science. It challenges the new institutionalism, probably the most significant present-day strand in both American and British political science. It moves away from such notions as 'bringing the state back in', 'path dependency' and modernist empiricism. Instead, Bevir and Rhodes argue for an anti-foundational analysis, ethnographic and historical methods...

with foreword by Michael X. Delli Carpini, Annenberg School for Communication, University of Pennsylvania, USAThis book critiques U.S. public policy about communication and offers guidelines to improve public safety and create strong democratic communities. The lack of effective emergency communication, basic information about health care, education, jobs and the economy, and civic life is at a crisis state, creating problems for the whole community, not just a vulnerable ...