This book reviews the latest advances in the development of silicon nano-biotechnology for biological and biomedical applications, which include biosensing, bioimaging, and cancer therapy. In this book, newly developed silicon nano-biotechnology and its biomedical applications are systematically introduced. For instance, fluorescent silicon nanoparticles, serving as novel high-performance biological nanoprobes, are superbly suited to real-time and long-term bioimaging. Silicon nanowire-bas...

This book demonstrates the power of mathematical thinking in understanding the biological complexity that exists within the brain. It looks at the latest research on modelling of biochemical pathways within synapses, and provides a clear background for the study of mathematical models related to systems biology. Discussion then focusses on developments in computational models based on networks linked to synaptic plasticity. The models are used to understand memory formation and impairment ...

This book offers readers an introduction to the current status of nanoparticles and other nanomaterials that have potential applications in theranostics. Above all, it highlights the diagnostic and therapeutic applications of metallic (e.g. Au, Ag), semiconducting quantum dots (e.g. CdSe, CdTe), magnetic (e.g. Fe3O4, FePt, Co), and multifunctional (combination of two or three) nanoparticles.

New insights into the evolution and nature of proteinsExploring several distinct approaches, this book describes the methods for comparing protein sequences and protein structures in order to identify homologous relationships and classify proteins and protein domains into evolutionary families. Readers will discover the common features as well as the key philosophical differences underlying the major protein classification systems, including Pfam, Panther, SCOP, and CATH. Moreover,...

"The story is told by THE inventor-pioneer-master in the field and is accompanied by amazing illustrations... [it] will become an absolute reference and a best seller in chemistry!"—Alberto Credi"... the great opus on the mechanical bond. A most impressive undertaking!"— Jean-Marie LehnCongratulations to co-author J. Fraser Stoddart, a 2016 Nobel Laureate in Chemistry.In molecules, the mechanical bond ...

Novel Optical Nanoprobes for Chemical and Biological Analysis starts with a brief introduction to several kinds of versatile nanomaterials with novel optical properties, such as gold/silver nanoparticles, quantum dots, upconversion nanoparticles and graphene. It mainly focuses on the latest sensor design strategies, which apply the optical properties of nanomaterials to various detection techniques including colorimetry, fluorescence, and surface-enhanced Raman scattering (SERS). ...

This book primarily focuses on the fundamentals of and new developments in electrochemiluminescence (ECL), presenting high-quality content and explicitly aiming to summarize and disseminate the current state-of-the-art. The topics covered include the fundamental theory, mechanism, types of reactions involved, and the instrumental techniques. The book also examines the applications of ECL in many of the emerging fields of science, such as bioanalytical, analytical, clinical, pharmaceutical,...

Unlike other handbooks in this emerging field, this guide focuses on the challenges and critical parameters in running a metabolomics study, including such often-neglected issues as sample preparation, choice of separation and detection method, recording and evaluating data as well as method validation. By systematically covering the entire workflow, from sample preparation to data processing, the insight and advice offered here helps to clear the hurdles in setting up and running a succes...

This book covers the recent advances in the development of bioelectronics systems and their potential application in future biomedical applications starting from system design to signal processing for physiological monitoring, to in situ biosensing.Advanced Bioelectronic Materials contributions from distinguished international scholars whose backgrounds mirror the multidisciplinary readership ranging from the biomedical sciences, biosensors and engineering communi...

Using chips composed of thousands of spots, each with the capability of holding DNA molecules corresponding to a given gene, DNA microarray technology has enabled researchers to measure simultaneously gene expression across the genome. As with other large-scale genomics approaches, microarray technologies are broadly applicable across disciplines of life and biomedical sciences, but remain daunting to many researchers. This guide is designed to demystify the technology and inform more biol...

Focusing on the practical applications, this user-oriented guide presents current technologies and strategies for systems-level lipidanalysis, going beyond basic research to concentrate on commercial uses of lipidomics in biomarker and diagnostic development, as wellas within pharmaceutical drug discovery and development. The editor and authors have experience of the most recent analytical instruments and techniques, allowing them to provide here first-hand practical experien...

Nano-scale materials are proving attractive for a new generation of devices, due to their unique properties. They are used to create fast-responding sensors with good sensitivity and selectivity for the detection of chemical species and biological agents. Nanosensors for Chemical and Biological Applications provides an overview of developments brought about by the application of nanotechnology for both chemical and biological sensor development. Part one addresses electrochemical nanosenso...