How genes are not the only basis of heredity—and what this means for evolution, human life, and diseaseFor much of the twentieth century it was assumed that genes alone mediate the transmission of biological information across generations and provide the raw material for natural selection. In Extended Heredity, leading evolutionary biologists Russell Bonduriansky and Troy Day challenge this premise. Drawing on the latest research, they demonstrate that wha...

Thirty years ago, biologists could get by with a rudimentary grasp of mathematics and modeling. Not so today. In seeking to answer fundamental questions about how biological systems function and change over time, the modern biologist is as likely to rely on sophisticated mathematical and computer-based models as traditional fieldwork. In this book, Sarah Otto and Troy Day provide biology students with the tools necessary to both interpret models and to build their own.The book star...

Consider the woven integrated complexity of a living cell after 3.8 billion years of evolution. Is it more awe-inspiring to suppose that a transcendent God fashioned the cell, or to consider that the living organism was created by the evolving biosphere? As the eminent complexity theorist Stuart Kauffman explains in this ambitious and groundbreaking new book, people who do not believe in God have largely lost their sense of the sacred and the deep human legitimacy of our inherited spiritua...

There is a widespread assumption that the universe in general, and life in particular, is 'getting more complex with time'. This book brings together a wide range of experts in science, philosophy and theology and unveils their joint effort in exploring this idea. They confront essential problems behind the theory of complexity and the role of life within it: what is complexity? When does it increase, and why? Is the universe evolving towards states of ever greater complexity and diversity...

In the hard sciences, which can often feel out of grasp for many lay readers, there are "great thinkers" who go far beyond the equations, formulas, and research. Minds such as Stephen Hawking philosophize about the functions and nature of the universe, the implications of our existence, and other impossibly fascinating, yet difficult questions. Stuart A. Kauffman is one of those great thinkers. He has dedicated his lifetime to researching "complex systems" at prestigious institutions and n...

The concepts of evolution and complexity theory have become part of the intellectual ether permeating the life sciences, the social and behavioral sciences, and, more recently, management science and economics. In this book, John E. Mayfield elegantly synthesizes core concepts from multiple disciplines to offer a new approach to understanding how evolution works and how complex organisms, structures, organizations, and social orders can and do arise based on information theory and computat...

An extensive update to a classic textStochastic geometry and spatial statistics play a fundamental role in many modern branches of physics, materials sciences, engineering, biology and environmental sciences. They offer successful models for the description of random two- and three-dimensional micro and macro structures and statistical methods for their analysis.The previous edition of this book has served as the key reference in its field ...

Unique in its clarity, examples and range, Physical Mathematics explains as simply as possible the mathematics that graduate students and professional physicists need in their courses and research. The author illustrates the mathematics with numerous physical examples drawn from contemporary research. In addition to basic subjects such as linear algebra, Fourier analysis, complex variables, differential equations and Bessel functions, this textbook covers topics such as the singular-value ...

This pioneering graduate textbook provides readers with the concepts and practical tools required to understand the maximum entropy principle, and apply it to an understanding of ecological patterns. Rather than building and combining mechanistic models of ecosystems, the approach is grounded in information theory and the logic of inference. Paralleling the derivation of thermodynamics from the maximum entropy principle, the state variable theory of ecology developed in this book predicts ...

This handbook and ready reference presents a combination of statistical, information-theoretic, and data analysis methods to meet the challenge of designing empirical models involving molecular descriptors within bioinformatics. The topics range from investigating information processing in chemical and biological networks to studying statistical and information-theoretic techniques for analyzing chemical structures to employing data analysis and machine learning techniques for QSAR/QSPR.

An accessible undergraduate textbook on the essential math concepts used in the life sciencesThe life sciences deal with a vast array of problems at different spatial, temporal, and organizational scales. The mathematics necessary to describe, model, and analyze these problems is similarly diverse, incorporating quantitative techniques that are rarely taught in standard undergraduate courses. This textbook provides an accessible introduction to these critical mathe...

Combining two important and growing areas of applied mathematics—control theory and modeling—this textbook introduces and builds on methods for simulating and tackling concrete problems in a variety of applied sciences.Emphasizing "learning by doing," the authors focus on examples and applications to real-world problems. An elementary presentation of advanced concepts, proofs to introduce new concepts, and carefully presented MATLAB® programs guide the reader through methods in opt...