Tsukasa, a college student, is rescued from an attack by a devil, one of many vampires that can blend in among the human population. Anzai, her savior, is a half-devil who exploits his supernatural gifts as a member of a shadowy police task force that specializes in devil-related crime in Tokyo. As Anzai continues to keep guard over Tsukasa, the two quickly forge a tentative bond-one that Anzai fears will test his iron-clad rule of never drinking human blood…

Anzai, suffering badly after a run-in with a sniper, is rescued at the last minute by a mysterious blond devil who gives him enough human blood to heal his wounds. Embarrassed by the way he lost control after tasting human blood, Anzai hides himself away from everyone, especially Tsukasa, until an incident unfolds live on broadcast TV which shines a glaring light on the devils who walk among the populace of Japan…

SURVIVE, THEY SAID. HAVE HOPE, THEY SAID. The world is no longer what it used to be. Shojo-ferocious, ape-like creatures who feed on humans-roam the land, and anyone who's bitten becomes infected with the same mysterious virus. Humanity has resisted by building aerial cities and forming special units called Guards to fight back. Among them, a young man with a blank stare battles without regard for his life-Minami. People call him a messiah, but their only hope has a constant death wish and...

Tsukasa insists on seeing that Oryo is cared for at a hospital, defying Anzai's wish that she stay hidden at their safe house. Before she can even make it inside the hospital, Tsukasa is taken hostage by a desperate Zero Seven, who eventually makes a surprisingly humane choice when facing off with her old comrades. Tsukasa and Anzai decide to take the next step in their relationship, and the old doctor from ONLO reveals why he's in town…

Anzai grapples with Lee's bombshell-that drinking human blood can have regenerative, strengthening powers on devil bodies-and Lee offers to share what he knows if Anzai's comrades hide him away. Meanwhile, Zero Seven, the sniper, faces the consequences of her rebellion as Zero Two works to tie up loose ends from the Ikebukuro incident, and reveals that he has an old connection to Anzai…

Dr. Kano sets up a “chance meeting” between the unsuspecting Anzai and his mother. Lee visits a blood donor as we catch a glimpse into his past at ONLO. Anzai's breach of the stand-down order has repercussions for F Squad, which gets a new leader, Ishimaru, who makes a surprising suggestion on how to handle the rogue Seven and Nine…

Ishimaru tries to bring in Zero Seven and Nine to get inside info on the CCC. In exchange for her cooperation, Zero Seven asks for information on the devil that murdered her mother, and the fateful meeting between Seven and Kikuhara is revealed. The house of an activist for devil rights is set on fire, and at the scene, Kikuhara pushes Anzai to remember his past…

Ishimaru, still shrouded in suspicion, leads F Squad on a raid of the CCC's hideout to get ahold of the list of members, but the CCC turns out to be several steps ahead in this cat-and-mouse game. When Anzai gets caught in the crossfire, Tsukasa has to make a life-or-death decision…

Minami, what would you do if Miyaji asked you to kill him? A new breed of shojo has invaded Pricketpolis. The city has fallen into chaos, and no one is safe. Some promise their loved ones that they will take their lives if they turn into a monster, while others refuse to. As Minami fights to protect the city, he must make a choice. Will he, or will he not, kill the people dear to him?

What does it mean to be alive? Minami-a young Guard who's rumored to be invincible-thinks about dying every day. In a world overrun by ape-like creatures called shojo, he has battled alone and thrown himself into all kinds of danger. And no matter what horror he's faced, he has betrayed no hints of fear, resentment, or despair. But when his newly assigned partner Miyaji gets bitten, Minami panics. He swings the Black Sword and severs Miyaji's leg to stop the infection from spreading and tu...

Anzai wakes up to find himself in the devil treatment floor of a hospital. While Anzai was unconscious he dreamt of his childhood at ONLO, and may have recalled a blocked memory involving both a young Kikuhara and his real father. As a result of the incident on the roof, the brass at the MPD have insisted that Tsukasa and Anzai be temporarily separated. Back full-time at school, Tsukasa makes an important discovery that will affect her future…

Anzai travels to Obihiro to learn the circumstances surrounding his birth as part of the Hybrid Plan, and the reason why Midori chose Tamaki for a partner. Tsukasa is also at ONL to read academic journals on devils, and both she and Anzai are notified that the “no contact” order is rescinded. As the two decide to take the next step within the clinical confines of the laboratory, Anzai begins to understand what drives him to chase after devils…