Targeted Therapy in Translational Cancer Research for the Translational Oncology series provides a comprehensive overview of recent developments in our understanding of tumor biology, elucidates the roles of targets and pathways involved in carcinogenesis, and describes current state-of-the-art anticancer therapy, as well as the most promising areas of translational research and targeted therapy.Introduces cutting-edge ‘bench to bedside and back’ breakthroug...

Non-equilibrium thermodynamics is a general framework that allows the macroscopic description of irreversible processes. This book introduces non-equilibrium thermodynamics and its applications to the rheology of multiphase flows. The subject is relevant to graduate students in chemical and mechanical engineering, physics and material science.This book is divided into two parts. The first part presents the theory of non-equilibrium thermodynamics, reviewing its essential features an...

This textbook provides a thorough presentation of the phenomena related to the transport of mass (with and without electric charge), momentum and energy. It lays all the basic physical principles, and then for the more advanced readers, it offers an in-depth treatment with advanced mathematical derivations and ends with some useful applications of the models and equations in specific settings.The important idea behind the book is to unify all types of transport phenomena, describin...

This textbook provides a thorough presentation of the phenomena related to the transport of mass, momentum and energy. It lays all the basic physical principles, then for the more advanced readers, it offers an in-depth treatment with advanced mathematical derivations and ends with some useful applications of the models and equations in specific settings.The important idea behind the book is to unify all types of transport phenomena, describing them within a common framework in ter...

This comprehensive book captures and compiles new and current information on hematologic malignancies. New knowledge of cellular disease processes, molecular pathology, and cytogenetic, epigenetic and genomic changes has influenced the current outlook toward haematological malignancies. This recent and ongoing expansion of knowledge on malignant hematology has not previously been utilized to its full capacity due to its diffuse distribution scattered over the internet and research publicat...

Tough Test Questions? Missed Lectures? Not Enough Time?Fortunately for you, there's Schaum's.More than 40 million students have trusted Schaum's to help them succeed in the classroom and on exams. Schaum's is the key to faster learning and higher grades in every subject. Each Outline presents all the essential course information in an easy-to-follow, topic-by-topic format. You also get hundreds of examples, solved problems, and practice exercises to test yo...

There has been major growth in understanding immune suppression mechanisms and its relationship to cancer progression and therapy. This book highlights emerging new principles of immune suppression that drive cancer, and it offers radically new ideas about how therapy can be improved by attacking these principles. Following work that firmly establishes immune escape as an essential trait of cancer, recent studies have now defined specific mechanisms of tumor immune suppression. It also dem...

This work will provide a historical perspective on tumor immunotherapy, discuss fundamental mechanisms of failed tumor rejection, look at passive strategies to boost anti-tumor immunity, as well as have an in-depth look at active strategies to boost anti-tumor immunity.

If you think projection operators work in the cinema, or learning about spin-1/2 makes your head, well, spin, Quantum Mechanics DeMYSTiFieD will energize your knowledge of this topic's fundamental concepts and theories, and allow you to learn at your own pace. This thoroughly revised and updated guide eases you into the subject, beginning with wave mechanics then introducing you to the mathematical foundations needed to do modern quantum physics. As you progress, you will lea...

This issue of the Surgical Oncology Clinics of North America, Guest Edited by Dr. William G. Cance, is devoted to Translational Cancer Research for Surgeons. Translational Cancer research aims to move bench research to the bedside by applying basic science toward potential therapies. This issue will present the concepts of translational research and development of targeted therapeutics, and its implications for surgeons. It will show clinical applications for surgeons regarding sarcoma/GIS...

The current state of the science supporting new research in lysophospholipidsThe study of lysophospholipids exploded with the discovery of cell surface receptors on both lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P). Since then, thousands of original research reports-ranging from fundamental cell signaling to the physiology and pathophysiology of individual organ systems-have centered on lysophospholipids. This book draws together and analyzes the c...

Updated to include the newest drugs and those currently in development, this Fifth Edition is a comprehensive reference on the preclinical and clinical pharmacology of anticancer agents. Organized by drug class, the book provides the latest information on all drugs and biological agents—their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance. The authors explain the rationale for use of drugs in specific schedules and combinations ...