Randomised Clinical Trials: Design, Practice and Reporting provides a detailed overview of the methodology for conducting clinical trials, including developing protocols, data capture, randomisation, analysis and reporting. Assuming no prior background, this user-friendly resource describes the statistical, regulatory, and practical components required for conducting randomised clinical trials. Numerous examples and case studies from industry, academia, and the research literature...

The assessment of patient reported outcomes and health-related quality of life continue to be rapidly evolving areas of research and this new edition reflects the development within the field from an emerging subject to one that is an essential part of the assessment of clinical trials and other clinical studies.The analysis and interpretation of quality-of-life assessments relies on a variety of psychometric and statistical methods which are explained in this book in a non-technic...

This is the first book to introduce the new statistics - effect sizes, confidence intervals, and meta-analysis - in an accessible way. It is chock full of practical examples and tips on how to analyze and report research results using these techniques. The book is invaluable to readers interested in meeting the new APA Publication Manual guidelines by adopting the new statistics - which are more informative than null hypothesis significance testing, and becoming widely us...

Featuring updates and revisions, the second edition of Clinical Neuropsychology provides trainee and practicing clinicians with practical, real-world advice on neuropsychological assessment and rehabilitation.Offers illustrated coverage of neuroimaging techniques and updates on key neuro-pathological findings underpinning neurodegenerative disordersFeatures increased coverage of specialist areas of work, including severe brain injury, frontotemporal lobar d...

More than forty years ago, Dr. Aaron T. Beck's pioneering Depression: Causes and Treatment presented the first comprehensive account of all aspects of depression and introduced cognitive therapy to health care providers and patients struggling with one of the most common and devastating diseases of the modern age. Since that classic text first appeared, the appreciation of the multifaceted nature of mood disorders has grown, and the phenomenological and biological aspects of psych...

This comprehensive workbook contains a variety of self-assessment methods that allow readers to test their statistical knowledge, put it into practice, and apply it in a medical context, while also providing guidance when critically appraising published literature. It is designed to support the best-selling third edition of Medical Statistics at a Glance, to which it is fully cross-referenced, but may ...

Modeled after Barbara Byrne’s other best-selling structural equation modeling (SEM) books, this practical guide reviews the basic concepts and applications of SEM using Mplus Versions 5 & 6. The author reviews SEM applications based on actual data taken from her own research. Using non-mathematical language, it is written for the novice SEM user. With each application chapter, the author "walks" the reader through all steps involved in testing the SEM model including:

The intersection between the fields of behavioral decision research and neuroscience has proved to be fertile ground for interdisciplinary research. Whereas the former is rich in formalized models of choice, the latter is rife with techniques for testing behavioral models at the brain level. As a result, there has been the rapid emergence of progressively more sophisticated biological models of choice, geared toward the development of ever more complete mechanistic models of behavior....

It is widely accepted that most psychiatric disorders are associated with cognitive impairment and that neuropsychological approaches can help unravel the mechanisms underlying brain function and help us develop a better understanding of these disorders. In this book, a panel of the world's leading experts describe the development of neuropsychological approaches to the investigation, description, measurement and management of a wide range of mental illnesses. Part One explains the rationa...

The human face is unique among social stimuli in conveying such a variety of different characteristics. A person's identity, sex, race, age, emotional state, focus of attention, facial speech patterns, and attractiveness are all detected and interpreted with relative ease from the face. Humans also display a surprising degree of consistency in the extent to which personality traits, such as trustworthiness and likeability, are attributed to faces. In the past thirty years, face perception ...

While most books on missing data focus on applying sophisticated statistical techniques to deal with the problem after it has occurred, this volume provides a methodology for the control and prevention of missing data. In clear, nontechnical language, the authors help the reader understand the different types of missing data and their implications for the reliability, validity, and generalizability of a study’s conclusions. They provide practical recommendations for designing studies that ...

Do statistics-heavy research papers give you a headache? Are you baffled by bias, confused by correlation, or flummoxed by F-tests? A Guide for the Statistically Perplexed is here to help! This book is designed to assist students, clinicians, and researchers in becoming familiar with statistical and research techniques by covering the essentials of the topic and drawing attention to many common problem areas.Inspired to write on this topic in reaction to mistakes he encoun...