Brazil changed drastically in the 21st century’s second decade. In 2010, the country’s outgoing president Lula left office with almost 90% approval. As the presidency passed to his Workers' Party successor, Dilma Rousseff, many across the world hailed Brazil as a model of progressive governance in the Global South. Yet, by 2019, those progressive gains were being dismantled as the far right-wing politician Jair Bolsonaro assumed the presidency of a bitterly divided country. Digging beneath...

Colloquial Burmese provides a step-by-step course in Burmese as it is written and spoken today. Combining a user-friendly approach with a thorough treatment of the language, it equips learners with the essential skills needed to communicate confidently and effectively in Burmese in a broad range of situations. No prior knowledge of the language is required.Key features include:progressive coverage of speaking, listening, reading and writing skills

The ras Superfamily of GTPases presents the most comprehensive compilation of information available regarding aspects of the putative function of small ras-related GTPases. The book's chapters were written by the world's most prominent scientists in this field and cover such topics as the structure and properties of ras proteins, ras function, the ras superfamily in general, and the functional regulation of ras and ras-related GTPases. The book will benefit cell biologists, oncologists, ne...

What does it take to write a good essay? This book covers the basics of grammar, sentence construction, and paragraphs, and then outlines how to plan and write an essay. You will find writing prompts, vocabulary lists, and editing exercises (with suggested answers).This text was written to accompany the online course of the same name, the first of two courses offered by College Writing Programs of the University of California, Berkeley through edX.org. For students in the course, t...

Yeast is one of the oldest domesticated organisms and has both industrial and domestic applications. In addition, it is very widely used as a eukaryotic model organism in biological research and has offered valuable knowledge of genetics and basic cellular processes. In fact, studies in yeast have offered insight in mechanisms underlying ageing and diseases such as Alzheimers, Parkinsons and cancer. Yeast is also widely used in the lab as a tool for many technologies such as two-hybrid ana...

Every time a cell divides, a copy of its genomic DNA has to be faithfully copied to generate new genomic DNA for the daughter cells. The process of DNA replication needs to be precisely regulated to ensure that replication of the genome is complete and accurate, but that re-replication does not occur. Errors in DNA replication can lead to genome instability and cancer. The process of replication initiation is of paramount importance, because once the cell is committed to replicate DNA, it ...

An unashamedly practical introduction to spoken Mandarin Chinese, for anyone who wants to impress their Chinese hosts, but doesn't have time to take a proper language course. Designed specifically for busy professionals traveling to China for work, it includes essential phrases that are easy to learn and pronounce, as well as invaluable cultural background. Heading off to China for a business trip? Don't know a word but want to impress? Grab One Minute Mandarin and make the most of your tr...

Cancer, which has become the second-most prevalent health issue globally, is essentially a malfunction of cell signaling. Understanding how the intricate signaling networks of cells and tissues allow cancer to thrive - and how they can be turned into potent weapons against it - is the key to managing cancer in the clinic and improving the outcome of cancer therapies. In their ground-breaking textbook, the authors provide a compelling story of how cancer works on the molecular level, and ho...

In clear, congenial style Barry Blake explains how language works. He describes the make-up of words and how they're built from sounds and signs and put together in phrases and sentences. He examines the dynamics of conversation and the relations between the sound and meaning. He shows how languages help their users connect to each other and to the world, how they vary around the world, why they never stop changing, and that no two people speak a language in the same way. He looks at how l...

The post-genomic era has brought new challenges and opportunities in all fields of the biology. In this context, several genome engineering technologies have emerged that will help deciphering genes function by as well as improve gene therapy strategies. Genomic modifications such as knock-in, knock-out, knock-down, sequence replacement or modification can today be routinely performed. However, in front of this large palette of methodologies scientists may experience difficulties to gather...

Learning to read a language with a foreign alphabet can be an intimidating challenge. Even before you can start to study the vocabulary and grammar, you must first decipher this strange new script.But learning a new alphabet does not have to be so difficult.Other language courses start by showing a table of the alphabet and then immediately proceed to dialogues and grammatical descriptions. This is not the ideal way to teach a foreign alphabet, and...

The study of epigenetics, or how heritable changes in gene expression are regulated without modifying the coding DNA sequence, has become an increasingly important field of study in recent years. Rapid developments in our understanding of the way in which gene function is modulated by the environment has revolutionized the way we think about human development and health. Nutrition in Epigenetics reviews the latest research looking at the interaction between genes and nutrients and...