Human Ageing: A Unique Experience explores the biology of human ageing focusing on the individual. The book begins with the premature ageing disorder Hutchinson-Gilford Progeria syndrome and spins a web of interconnected biological domains involving lamins, telomeres, alternative splicing, genetics, epigenetics, and molecular clocks. The profound influence of culture is explored since cultural inheritance and genetic inheritance are the two intertwined processes driving human evolution. An...

NEW YORK TIMES BESTSELLER • From the author of The Untethered Soul and Living Untethered comes the astonishing true-life story about the spiritual harmony and personal happiness he found when he just let go.“With his hallmark precision and clarity Michael Singer reveals how everyday life, doing business in the world, and spiritual practice can be synchronized to carry us into the heart of life’s unimaginable perfection.”—Jack Canf...

Your awareness of uncommon diseases and possible complications is vital to successful anesthetic patient management. Anesthesia and Uncommon Diseases, 6th Edition, brings you up to date with new information on less commonly seen diseases and conditions, including the latest evidence and management guidelines. This unique medical reference book is essential for a complete understanding of today’s best options and potential difficulties in anesthesia.Improve your ability to...

Tuberculosis is an ancient disease, but it's not a disease of history. With more than a million victims every year – more than any other disease, including malaria – and antibiotic resistance now found in every country worldwide, tuberculosis is once again proving itself to be one of the smartest killers humanity has ever faced. But it's hardly surprising considering how long it's had to hone its skills. Forty-thousand years ago, our ancestors set off from the cradle of ci...

" HOW TO UNDERSTAND THE RIPPLE ON EFFECT OF MENIERE'S DISEASE. AND BE A MENIERE SURVIVOR."The Author's personal 'solo-recovery' (without surgery) is a groundbreaking success story. But along with recovery, another catastrophe happened. He fought Meniere's and recovered his physical health, but lost the fight to save his material world; the family home, future assets and his business career.This is the book HE wishes someone had written for him!Menie...

Substance use and addiction is an increasing problem amongst older people. The identification of this problem is often more difficult in older patients and is frequently missed, particularly in the primary care context and in emergency departments, but also in a range of medical and psychiatric specialties.Substance Use and Older People shows how to recognise and treat substance problems in older patients. However, it goes well beyond assessment and diagnosis by incorporat...

This issue of Clinics in Geriatric Medicine, guest edited by Dr. Elsa S. Strotmeyer, is devoted to Medical Complications of Diabetes in Older Adults. Articles in this issue include: Glucose Dysregulation: Pathophysiology and Prevention; Diabetic Medications and Polypharmacy; Physical Function and Disability; Diabetes and Osteoarthritis; Adiposity, Muscle Mass, and Diabetes; Exercise and Weight Loss in Diabetes Management; Diabetes and Cognition; Diabetes and Depression; Sleep Apnea and Dia...

This issue of Clinics in Geriatric Medicine focuses on the pharmacological, non-pharmacological, and device therapies in the medical management of cardiac rhythm disorders in the elderly population. It also reviews the epidemiology of arrhythmias and conduction disorders in older adults, atrial fibrillation and atrial flutter: stroke prevention, bradyarrhythmias and conduction disorders, and comorbidities, quality of life, and end-of-life issues in older patients with heart rhythm disorder...

Metabolic bone degeneration (osteoporosis) affects millions of people--primarily postmenopausal women--and is directly responsible for debilitating hip, vertebral, and limb fractures in the elderly. Incorporating advances made within just the past five years, The Osteoporotic Syndrome: Detection, Prevention, and Treatment serves as an up-to-date, practical guide to the major clinical aspects of osteoporosis. The text is liberally illustrated with detailed figures. As a resource for the cli...

Providing scientifically accurate, detailed, and accessible information to students and general readers, this book presents the history of vaccination; describes the administration, manufacturing, and regulation of vaccines in the United States; and explains the most recent scientific findings about vaccination while addressing concerns of those who oppose immunization.What is a vaccine and how does it work? How are vaccines made? Who discovered vaccines? What diseases do vaccines ...

This book presents state of the art knowledge and practice in the rapidly developing field of bronchiectasis not due to cystic fibrosis. The focus is especially on diagnosis and existing and emerging therapies, but the book also covers a wide range of other key topics, from pathophysiology, histopathology, and immunology through to pulmonary rehabilitation, nursing care, and management in primary care and pediatric settings.While non–cystic fibrosis bronchiectasis was formerly rega...

This issue of Immunology and Allergy Clinics of North America, Guest Edited by Amy D. Klion, MD and Princess U. Ogbogu, MD, is devoted to Eosinophil-Associated Disorders. Drs. Klion and Ogbogu have assembled a group of expert authors to review the following topics: Evaluation and Differential Diagnosis of Persistent Marked Eosinophilia; Spectrum of Eosinophilic End Organ Manifestations; Eosinophilia in GI disorders; Eosinophilia in Hematologic Disorders; Eosinophilia in Rheumatologic/Vascu...