This established handbook is unique in illustrating and reviewing the cell and extracellular matrix, organelle by organelle (with numerous subsections) with emphasis on human pathology. Anyone studying normal or pathological tissues whether human, animal, or tissue culture, by conventional transmission electron microscopy for diagnosis or research, will use this book to understand what it is they are examining—without having to go through large volumes of previously published articles....

The relentless pace of innovation in biomedical imaging has provided modern researchers with an unprecedented number of techniques and tools to choose from. While the development of new imaging techniques is vital for ongoing progress in the life sciences, it is challenging for researchers to keep pace. Imaging Modalities for Biological and Preclinical Research is designed to provide a comprehensive overview of currently available biological and preclinical imaging methods, includ...

Brings a fresh point of view to the current state of correlative imaging and the future of the fieldThis book provides contributions from international experts on correlative imaging, describing their vision of future developments in the field based on where it is today. Starting with a brief historical overview of how the field evolved, it presents the latest developments in microscopy that facilitate the correlative workflow. It also discusses the need for an ide...

Volume Electron Microscopy (vEM), Volume 177 is a collective term for a set of three-dimensional high-resolution ultrastructural imaging techniques that have delivered new insights into biological systems in recent years, garnering substantial interest in the life and clinical sciences. In this book, users will find a variety of vEM workflows and technologies, highlighting application areas with biologically relevant examples. Topics covered include Automated large volume sample preparatio...