Obesity is a worldwide epidemic that affects half a billion people. It has been estimated that, if current trends continue, by 2050, 60% of men and 50% of women worldwide will be obese. Hypertrophy and hyperplasia of white adipose tissue caused by overweight and obesity lead to a chronic inflammatory state, which results in impaired insulin sensitivity and the development of diabetes. Currently, the number of people affected by diabetes globally exceeds 400 million (rising more rapidly in ...

Although transgender persons have been present in various societies throughout human history, it is only during the last several years that they have become widely acknowledged in our society and their right to quality medical care has been established. In the United States, endocrinologists have been providing hormonal therapy for transgender individuals for decades; however, until recently, there has been only limited literature on this subject, and non-endocrine aspects of medical care ...

"Principles of Diabetes Mellitus, Second Edition" is an important update to the comprehensive textbook first published in 2002 and reissued in 2004. It is written for physicians of all specialties who, on a daily basis, deal with an illness which has reached epidemic proportions. The book is also intended for medical students and investigators of all aspects of diabetes.The last five years have witnessed major developments in our understanding of diabetes and in therapeutic approac...

This issue of Endocrinology Clinics brings the reader up to date on the important advances in research surrounding acute diabetic complications. Guest edited by Leonid Poretsky and Eliana Liao, the topics covered include retinopathy, neuropathy, gastrointestinal complications, diabetic foot, dental complications, dermatologic complications, and more.

This issue of the Endocrinology and Metabolism Clinics, guest edited by Drs. Leonid Poretsky and Emilia Pauline Liao, will focus on Diabetes Mellitus: Associated Conditions. Articles in this issue include Metabolic syndrome; The role of glucocorticoids and insulin resistance in adipose tissue function and lipid metabolism; Cardiovascular disease; The Relationships between Cardiovascular Disease and Diabetes: Focus on Pathogenesis; Interventions for coronary artery disease; Peripheral Arter...

Essential Pain Pharmacology: The Prescriber's Guide expertly reviews the most important medications used to relieve pain, now considered by many physicians as the fifth vital sign. The catalogue of analgesics has expanded rapidly, and this text presents the most up-to-date, comprehensive array of agents available for prescribing. Each clear and concise drug entry covers the range of indications, advantages and disadvantages, and tips for appropriate dosing and avoiding adverse effects. A s...

Endorsed by the American Society for Preventive Cardiology! Preventive Cardiology - a new Companion to Braunwald's Heart Disease - addresses the prevention and risk stratification of cardiovascular disease so that you can delay the onset of disease and moderate the effects and complications. Drs. Roger Blumenthal, JoAnne Foody, and Nathan Wong discuss the full range of relevant considerations, including the epidemiology of heart disease, risk assessment, risk factors, multiple risk factor-...

Clinical Dilemmas in Diabetes provides evidence-based clinical guidance on the most common and problematic areas of concern encountered in diagnosing, treating and managing patients with diabetes. Each chapter is highly topical and has been selected due to current interest, specific recent developments, and areas of controversy.This valuable guide provides assistance in managing the life-long treatment of diabetes and the complications that often develop in patient...

The prevalence of hypertension is almost three times as high as that of diabetes mellitus type 2, with both conditions being major risk factors for stroke, ischemic heart disease, cardiac arrhythmias, and heart failure. The exact prevalence of hypertension related to hormonal derangements (endocrine hypertension) is not known but estimated to affect less than 15% of hypertensive patients. Recent scientific discoveries have increased the understanding of the pathophysiologic mechanisms of h...

The International Textbook of Diabetes Mellitus has been a successful, well-respected medical textbook for almost 20 years, over 3 editions. Encyclopaedic and international in scope, the textbook covers all aspects of diabetes ensuring a truly multidisciplinary and global approach. Sections covered include epidemiology, diagnosis, pathogenesis, management and complications of diabetes and public health issues worldwide. It incorporates a vast amount of new data regarding the scien...

Now in its fifth edition, the Textbook of Diabetes has established itself as the modern, well-illustrated, international guide to diabetes. Sensibly organized and easy to navigate, with exceptional illustrations, the Textbook hosts an unrivalled blend of clinical and scientific content. Highly-experienced editors from across the globe assemble an outstanding set of international contributors who provide insight on new developments in diabetes care and inf...

This field has shown tremendous growth in recent years, primarily due to the recognition that drug-induced liver disease is the most common cause of liver failure and one of the major contributors to the withdrawal of drugs developed by the pharmaceutical industry. Drug-Induced Liver Disease, 3rd edition is a comprehensive reference that covers mechanisms of injury, diagnosis and management, major hepatotoxins, regulatory perspectives and much more. Written by highly respected authorities,...