In the past 2 decades, the introduction of biologic therapies that target underlying disease processes has dramatically changed the treatment of the inflammatory bowel diseases (IBDs), ulcerative colitis and Crohn’s disease. Current biologic therapy with tumor necrosis factor inhibitors and anti-integrins has improved the treatment of IBD flares and maintenance of clinical remission. These agents are, however, limited by primary nonresponse and loss of response in a substantial proportion ...

Homeland Defense is one of the most, if not THE most important issues of our time. Repeated and widely reported failures of our security have become almost too commonplace and Federal officials have conceded that another terrorist attack on our soil is almost inevitable.Now, B. Raymond Gary spotlights this issue with his all-too-possible, and very probable Novel, Compound Target, a scenario of a terrorist attempt to deliver and detonate a device in a large city in the Nati...

As Peter Jackson’s cinematic hobbits set forth, 3-Minute Tolkien celebrates the enduring influence of the world’s most revered fantasy writer. It offers a readable, absorbing structure, dividing J.R.R. Tolkien’s life and cultural contribution into 60 neat portions, every one digestible in a mere three minutes: 20 mini-sections each on Life, Work and Influence.From a childhood inventing new languages in the sylvan landscape of the Severn valley, through a First World War that saw hi...

Home to You is a celebratory anthology of new, thought-provoking nonfiction from leading writers that Wales Arts Review has featured in its first ten years. Our contributors originate from both inside and outside Wales, and many live beyond its borders, but all have their reasons to call the nation home.

Imagine a world devoid of violence—a world where fists can’t hit, guns don’t kill, and bombs can’t destroy. In this tantalizing novel of possibility, this has—suddenly and inexplicably—become our new reality. The U.S. president must find a new way to wage war. The Pope ponders whether the Commandment “Thou Shalt Not Kill” is still relevant. A dictator takes his own life after realizing that the violence he used to control his people is no longer an option. In the first days after the chang...

This is an ethnographic collection of 12 edited talks and conversations from a conference on violence, conflict, and the world order held at Eastern Kentucky University. The conference was organized by Carole Garrison, Chair of Criminal Justice and Police Studies at EKU, who arranged for video recording and transcription of the talks and conversations. The collection is divided into two parts: domestic and global issues. Some of the topics examined include violence against women, restricti...

The inspiration for the film Total Recall, starring Colin Farrell and Kate Beckinsale, and directed by Len Wiseman. This ebook-only edition of Philip K. Dick’s classic short story tells the story of Douglas Quail, an unfulfilled bureaucrat who dreams of visiting Mars, but can't afford the trip. Luckily, there is Rekal Incorporated, a company that lets everyday stiffs believe they’ve been on incredible adventures. The only problem is that when technicians attempt a memory implant o...

An enthralling collection of nonfiction essays on a myriad of topics—from art and artists to dreams, myths, and memories—observed in #1 New York Times bestselling author Neil Gaiman’s probing, amusing, and distinctive style.An inquisitive observer, thoughtful commentator, and assiduous craftsman, Neil Gaiman has long been celebrated for the sharp intellect and startling imagination that informs his bestselling fiction. Now, The View from the Cheap Seats brings tog...

Two decades ago The Trouble with Canada sparked a conservative renewal and inspired a generation.Now, in this completely revised update, William D. Gairdner rejoins the battle, showing that Canada suffered a disturbing regime change in the last quarter of the twentieth century and is now caught between two irreconcilable styles of government: top-down collectivism and bottom-up individualism.The result is a regime besotted with high taxation and big government, a w...

This revised and updated examination of how J.R.R.Tolkien came to write his original masterpiece The Hobbit includes his complete unpublished draft version of the story, together with notes and illustrations by Tolkien himself.The Hobbit was first published on 21 September 1937. Like its sequel, The Lord of the Rings, it is a story that ‘grew in the telling’, and many characters and plot threads in the published text are quite different f...

"Giroux refuses to give in or give up. The Violence of Organized Forgetting is a clarion call to imagine a different America--just, fair, and caring--and then to struggle for it."--Bill Moyers"Henry Giroux has accomplished an exciting, brilliant intellectual dissection of America's somnambulent voyage into anti-democratic political depravity. His analysis of the plight of America's youth is particularly heartbreaking. If we have a shred of moral fibre left in our beings, H...

Build a Believable WorldHow essential is setting to a story? How much description is too much? In what ways do details and setting tie into plot and character development? How can you use setting and description to add depth to your story?You can find all the answers you need in Write Great Fiction: Description & Setting by author and instructor Ron Rozelle. This nuts-and-bolts guide - complete with practical exercises at the end o...