Use PhoneGap to apply web development skills and learn variety of cross-platform mobile applicationsKey FeaturesBook DescriptionPhoneGap is a free and open source framework that allows you to create mobile apps using standardized web APIs for the platforms you care about. It is one of the first and fastest spreading tools to develop hybrid applications using CSS, JavaScript, and HTML, without losing the advantages of native applications. If you are alr...

The biennial TNF-family conferences have been held over the past 20 years, from the time that TNF was cloned. These meetings have followed the enormous progress in this field. Much is now known about the members of the TNF ligand and receptor families, their signaling proteins, mechanisms of action and cellular functions. This volume is the proceedings of the 12th TNF International Conference, held in April 2009. This conference focuses on the physiological, pathophysiological, and medical...

This Wrox Blox is a value-packed resource to help experienced .NET developers learn the new .NET release. It is excerpted from the Wrox books: Professional C# 4 and .NET 4, Professional ASP.NET 4, and WPF Programmer’s Reference by Christian Nagel, Bill Evjen, Scott Hanselman, and Rod Stephens, and includes more than 100 print book pages drawn from these three key titles. It is an excellent resource to help .NET developers get up to speed fast on .NET 4, C# 4.0, ASP.NET 4, and WPF,...

There has been major growth in understanding immune suppression mechanisms and its relationship to cancer progression and therapy. This book highlights emerging new principles of immune suppression that drive cancer, and it offers radically new ideas about how therapy can be improved by attacking these principles. Following work that firmly establishes immune escape as an essential trait of cancer, recent studies have now defined specific mechanisms of tumor immune suppression. It also dem...

Learn Visual Basic step by step and start programming right awayBeginning Visual Basic 2015 is the ideal guide for new programmers, especially those learning their first language. This new edition has been updated to align with Visual Studio 2015, and also refocused to concentrate on key beginner topics. Precise, step-by-step instructions walk you through important tasks, and clear explanations targeted to beginners will have you writing your first Visual ...

Glioblastoma is the most malignant brain tumor that still remains incurable. It is such a deadly disease that patients do not survive more than a few months after diagnosis. Our understanding of the histopathology and molecular mechanisms of formation of glioblastoma is rapidly advancing so as to provide us clues for devising rational therapeutic strategies for treatment of this malignancy. It is important that we continue to improve our knowledge about the pathogenesis of this devastating...

Targeted Therapy in Translational Cancer Research for the Translational Oncology series provides a comprehensive overview of recent developments in our understanding of tumor biology, elucidates the roles of targets and pathways involved in carcinogenesis, and describes current state-of-the-art anticancer therapy, as well as the most promising areas of translational research and targeted therapy.Introduces cutting-edge ‘bench to bedside and back’ breakthroug...

In-depth coverage of the major Visual Studio 2015 revampProfessional Visual Studio 2015 is the leading pro's guide to new and upgraded features of Microsoft Visual Studio. With a unique IDE-centric approach and deep dive into the software's many nooks and crannies, this book will bring you up to speed quickly on everything Visual Studio 2015 has to offer. Whether you're new to Visual Studio or just upgrading, you'll appreciate in-depth, professional explan...

This comprehensive volume explores the latest research on the mechanisms of resistance in cancer cells to CTL-mediated immunotherapy. Chapter topics discuss cell-mediated immunity as the result of cytotoxic T-lymphocytes (CTL) directed specifically against cancer cells. In addition, the volume reviews how CTL mediate the cytotoxic activity, in large part, by the indication of apoptosis; hence, tumor cells develop anti-apoptotic mechanisms and thereby, resist CTL-induced apoptosis. In order...

Updated to include the newest drugs and those currently in development, this Fifth Edition is a comprehensive reference on the preclinical and clinical pharmacology of anticancer agents. Organized by drug class, the book provides the latest information on all drugs and biological agents—their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance. The authors explain the rationale for use of drugs in specific schedules and combinations ...

Squamous cell cancers of the head and neck (SCCHN), also known as head and neck cancers (HNC) encompass malignancies of the oral cavity, larynx, nasopharynx and pharynx, and are diagnosed in over 500,000 patients worldwide each year, accounting for 5% of all malignancies. In the past several years, there have been significant developments in understanding of HNC. It is now recognized that although alcohol and tobacco use has represented the likely predominant cause of SCCHN, the incidence ...

GNU Emacs is the most popular and widespread of the Emacs family of editors. It is also the most powerful and flexible. Unlike all other text editors, GNU Emacs is a complete working environment--you can stay within Emacs all day without leaving. Learning GNU Emacs, 3rd Edition tells readers how to get started with the GNU Emacs editor. It is a thorough guide that will also "grow" with you: as you become more proficient, this book will help you learn how to use Emacs more effectiv...