Dr. Reuben provides a timely update to the topic of HCC, which was last covered in 2011. The highly respected authors in his issue address advances in imaging for diagnosis, surgical resection and liver transplantation, and local and systemic therapy. The breadth of the topic is covered, with articles devoted to histopathology, classification and staging, and screening and detection.

Geared toward both beginning and advanced undergraduate and graduate students, this self-contained treatment offers an elementary approach to finite projective planes. Following a review of the basics of projective geometry, the text examines finite planes, field planes, and coordinates in an arbitrary plane. Additional topics include central collineations and the little Desargues' property, the fundamental theorem, and examples of finite non-Desarguesian planes.Virtually no knowled...

The conditions of Crohn’s disease and ulcerative colitis are excellent examples of how the exponential growth of knowledge in biomedical science can make a remarkable impact on clinical practice and patient’s quality of life. It has led to the development of unique novel immunomodulatory treatments. These are continuously being refined to treat not only the two original conditions in the gut, but the systemic immunologic illness with its associated extraintestinal disorders. New therapies ...

It is now widely accepted that multidisciplinary collaboration and multimodality treatment approaches are important in improving the survival of patients with hepatocellular carcinoma. In this comprehensive textbook, internationally renowned experts in the field present and discuss the various strategies employed in the treatment of the disease. Up-to-date information is provided on the indications for and outcome of a range of treatment options, including surgical resection, liver transpl...

Hemostasis and Thrombosis: Practical Guidelines in Clinical ManagementEdited byHussain I Saba MD, PhDProfessor of MedicineDirector of Hematology/Hemophilia/Hemostasis & Thrombosis CenterUSF College of MedicineProfessor EmeritusDepartment of Malignant HematologyMoffitt Cancer Center and Research InstituteTampa, FL, USAHarold R Roberts MDEmeritus Professo...

Tumor Board Review utilizes the knowledge and expertise of oncology specialists to enhance learning the practice of oncology. Each of the 32 chapters follows a uniform format: a concise summary of the epidemiology, risk factors, natural history, and pathology of each major organ-specific tumor type; an abbreviated display of the relevant staging (generally based on the American Joint Commission on Cancer [AJCC] Staging, 7th Edition); and several Ïtumor boardÒstyleÓ illust...

Written by clinicians from the National Cancer Institute and other leading institutions, this comprehensive, clear, concise oncology handbook is designed specifically for quick bedside consultation. It covers all malignancies and offers busy clinicians practical guidelines on daily patient management, including commonly used treatment regimens and chemotherapy dosing and schedules. The user-friendly format features tables, charts, bullet points, and algorithms. The thoroughly updated Third...

Dr. Adrian Reuben updates one of the most highly requested topics in liver disease by inviting highly distinguished authors to address the important aspects of diagnosis and treatment of hepatocelluar carcinoma. State-of-the-art issues are addressed, including the role of oncogenic viruses, molecular and genetic guidelines, and screening and staging. Dr. Reuben, himself, concludes the issue with an important article on an agorithmic approach to diagnosis and treatment: Resect, Ablate, Repl...

This book provides a thorough and up-to-date discussion of key issues in the supportive care of children with cancer. A variety of frequently encountered situations is covered, including infections, metabolic, cardiopulmonary and neurologic emergencies, tumor lysis syndrome, pain, emesis, mucositis, thrombotic disorders, nutritional problems, hyperleukocytosis and acute abdomen. Throughout the emphasis is firmly on evidenced-based guidance developed from the relevant literature. Informatio...

This book reviews the recent progress made in the prevention, diagnosis, and treatment of esophageal cancer. Epidemiology, molecular biology, pathology, staging, and prognosis are first discussed. The radiologic assessment of esophageal cancer and the role of endoscopy in diagnosis, staging, and management are then described. The principles of surgical resection, radiation therapy, and systemic chemotherapy for esophageal cancer are explained, and particular attention is paid to the multid...

As there is a high incidence of disease recurrence after liver transplantation, this volume is designed around the need for a reference text dealing exclusively with this problem. The book places special emphasis on pre- and post-transplant predictors of recurrence, severity assessment, prophylaxis, and treatment. Pathobiology of disease recurrence is discussed in detail where applicable. Issues including quality of life and cost burden are also covered in the text.Written by well-...

Clinical Neuroimmunology: Multiple Sclerosis and Related Disorders serves as an indispensable resource for physicians interested in, and dealing with, this very complex and evolving branch of neurology. This comprehensive titleprovides an introduction to basic neuroimmunology and principles of immunotherapy and also serves as a thorough guide to immune-mediated disorders of the central and peripheral nervous system, as well as other systemic disorders with a significant neuroimmun...