Computer models offer a means of interpreting and analyzing the dynamics of real-world systems ranging from population growth to ozone depletion and a new section on modeling in genetics. Dynamic Modeling introduces an approach to modeling that makes it a more practical, intuitive endeavor. The book enables readers to convert their understanding of a phenomenon to a computer model, and then to run the model and let it yield the inevitable dynamic consequences built into the structure of th...

This book explores how PPPM, clinical practice, and basic research could be best served by information technology (IT). A use-case was developed for hepatocellular carcinoma (HCC). The subject was approached with four interrelated tasks: (1) review of clinical practices relating to HCC; (2) propose an IT system relating to HCC, including clinical decision support and research needs; (3) determine how a clinical liver cancer center can contribute; and, (4) examine the enhancements and impac...

Medical Imaging Informatics provides an overview of this growing discipline, which stems from an intersection of biomedical informatics, medical imaging, computer science and medicine. Supporting two complementary views, this volume explores the fundamental technologies and algorithms that comprise this field, as well as the application of medical imaging informatics to subsequently improve healthcare research. Clearly written in a four part structure, this introduction follows na...

This book portrays the commonality of tissue micro-structure that dictates physiological function in various organs (microstructure-function relation). Tissue and organ models are used to illustrate physiological functions based on microstructure. Fiber scale properties such as orientation and crimp are described in detail. Structurally-based constitutive models are given throughout the book, not only to avoid ambiguities in material characterization, but also to offer insights into the fu...

This book presents an overview of a variety of contemporary statistical, mathematical and computer science techniques which are used to further the knowledge in the medical domain. The authors focus on applying data mining to the medical domain, including mining the sets of clinical data typically found in patient’s medical records, image mining, medical mining, data mining and machine learning applied to generic genomic data and more. This work also introduces modeling behavior of cancer ...

Approaches in Integrative Bioinformatics provides a basic introduction to biological information systems, as well as guidance for the computational analysis of systems biology. This book also covers a range of issues and methods that reveal the multitude of omics data integration types and the relevance that integrative bioinformatics has today. Topics include biological data integration and manipulation, modeling and simulation of metabolic networks, transcriptomics and phenomics...

This book addresses the key issues in the modeling and simulation of diffusive processes from a wide spectrum of different applications across a broad range of disciplines. Features: discusses diffusion and molecular transport in living cells and suspended sediment in open channels; examines the modeling of peristaltic transport of nanofluids, and isotachophoretic separation of ionic samples in microfluidics; reviews thermal characterization of non-homogeneous media and scale-dependent por...

This volume constitutes the papers presented at the 15th International Conference on Computer Aided Systems Theory, EUROCAST 2015, held in February 2015 in Las Palmas de Gran Canaria, Spain.The total of 107 papers presented were carefully reviewed and selected for inclusion in the book. The contributions are organized in topical sections on Systems Theory and Applications; Modelling Biological Systems; Intelligent Information Processing; Theory and Applications of Metaheuristic Alg...

This invaluable text/reference reviews the state of the art in simulation-based approaches across a wide range of different disciplines, and provides evidence of using simulation-based approaches to advance these disciplines. Highlighting the benefits that simulation can bring to any field, the volume presents case studies by the leading experts from such diverse domains as the life sciences, engineering, architecture, arts, and social sciences.Topics and features: includes review ...

These Proceedings of the 2015 MICCAI Workshop “Computational Diffusion MRI” offer a snapshot of the current state of the art on a broad range of topics within the highly active and growing field of diffusion MRI. The topics vary from fundamental theoretical work on mathematical modeling, to the development and evaluation of robust algorithms, new computational methods applied to diffusion magnetic resonance imaging data, and applications in neuroscientific studies and clinical practice.

This book constitutes the refereed proceedings of the 15th International Conference on Computational Methods in Systems Biology, CMSB 2017, held in Darmstadt, Germany, in September 2017. The 15 full papers, 4 tool papers and 4 posters presented together with 1 invited talk were carefully reviewed and selected from 41 regular paper submissions. Topics of interest include formalisms for modeling biological processes; models and their biological applications; frameworks for model verication, ...

This book integrates current advances in biology, economics of information and linguistics research through applications using agent-based modeling and social network analysis to develop scenarios of communication and language emergence in the social aspects of biological communications. The book presents a model of communication emergence that can be applied both to human and non-human living organism networks. The model is based on economic concepts and individual behavior fundamental fo...