How to identify optimal phase II trial designsProviding a practical guide containing the information needed to make crucial decisions regarding phase II trial designs, A Practical Guide to Designing Phase II Trials in Oncology sets forth specific points for consideration between the statistician and clinician when designing a phase II trial, including issues such as how the treatment works, choice of outcome measure and randomization, and considering both ...

This story is part of Reading Champion, a series carefully linked to book bands to encourage independent reading skills, developed with Dr Sue Bodman and Glen Franklin of UCL Institute of Education (IOE)Jumping in Puddles shows Harry, who loves jumping in puddles, find a puddle deeper than he thought!Reading Champion offers independent reading books for children to practise and reinforce their developing reading skills.Fantastic, original s...

The Social Protests of 2020: Visceral Responses to Police Brutality, COVID-19, and Circumscribed Sexuality collects voices from various Black intellectuals — university professors, a scientist, media communication specialist, poets, a visual artist, and political activists — to illustrate how the simultaneity of high-profile political events in the summer of 2020 manifest in our consciousness at one time. Reflecting the contributors’ honest visceral responses, the chapters reveal the angui...

England, 1685. Decades after the end of the civil war, the country is once again divided when Charles II's illegitimate son, the Protestant Duke of Monmouth, arrives in Dorset to incite rebellion against his Catholic uncle.Armed only with pitchforks, Monmouth's army is quickly defeated by King James II's superior forces and charged with high treason. Those found guilty will be hanged, drawn and quartered.As Dorset braces for carnage, the redoubtable Lady Jayne Harrier and a...

Miracles can and do happen— when one does the footwork. Dr. Walter Turnbull dreamed of creating opportunities and better lives for the children of Harlem, and Lift Every Voice is the inspirational story of how he realized his dream. Dr. Turnbull shares the hard-bought wisdom he learned throughout his life— from his impoverished childhood in backwoods Mississippi to his experiences as founder and director of the Grammy Award-winning Boys Choir of Harlem. Turnbull shares insights on...

Craig and Tom have been friends since second grade, but that was five years ago and Craig is getting sick of Tom's out-of-bounds behavior.When Craig begins to realize that he may have more potential in school than he ever thought, he starts to distance himself from Tom, who is both the class clown and the school bully. But severing ties with an old friend is never easy, and a foolhardy incident in a local park pulls Craig back into Tom's orbit. Faced with the reali...

PAGE is a Tkinter-based GUI designer for Python, available for free and as an open-source tool. It generates native Python code, enabling users to swiftly create Graphical Interfaces for their Python programs. If you're eager to delve into GUI development for your Python programs, then this book is your go-to resource. This comprehensive book is your guide from installing the PAGE designer to mastering the creation of complex GUI interfaces. It covers a wide range of topics, from building ...

Dorset, 1642.When bloody civil war breaks out between the King and Parliament, families and communities across England are riven by different allegiances.A rare few choose neutrality.One such is Jayne Swift, a Dorset physician from a Royalist family, who offers her services to both sides in the conflict. Through her dedication to treating the sick and wounded, regardless of belief, Jayne becomes a witness to the brutality of war and the devastation it wreaks.

This story is part of Reading Champion, a series carefully linked to book bands to encourage independent reading skills, developed with Dr Sue Bodman and Glen Franklin of UCL Institute of Education (IOE)The Cat and the Cradle is a retelling of a Dutch tale, in which a baby is washed away in a storm and is rescued by a very brave cat.Reading Champion offers independent reading books for children to practise and reinforce their developing reading ski...

When Jack Dorsey returned to Twitter as CEO in 2015, the company was in trouble. But unlike so many other social media platforms that have crumbled under tough conditions, Twitter is still alive—and thriving.How did Twitter turn itself around in one of the most turbulent and competitive industries? The change management approach of authors Gregory P. Shea and Cassie A. Solomon guided a significant area of the organization's turnaround effort.In this revised...

This dazzling anthology includes epic interstellar adventures, tales of space and wonder, from some of the brightest names in science fiction. Authors includeKage BakerStephen BaxterGregory BenfordTony DanielGreg EganPeter F. HamiltonGwyneth JonesJames Patrick KellyNancy KressKen MacleodPaul J. McAuleyIan McDonaldRobert ReedAlastair ReynoldsMary RosenblumRobert SilverbergDan SimmonsWalter Jon Williams

Translating the evidence from the bedside to populationsThis sixth edition of the best-selling Epidemiology, Evidence-based Medicine and Public Health Lecture Notes equips students and health professionals with the basic tools required to learn, practice and teach epidemiology and health prevention in a contemporary setting.The first section, 'Epidemiology', introduces the fundamental principles and scientific basis behind work to improve the healt...