This book features research contributions from The Abel Symposium on Statistical Analysis for High Dimensional Data, held in Nyvågar, Lofoten, Norway, in May 2014.The focus of the symposium was on statistical and machine learning methodologies specifically developed for inference in “big data” situations, with particular reference to genomic applications. The contributors, who are among the most prominent researchers on the theory of statistics for high dimensional inference, prese...

The growth of biostatistics has been phenomenal in recent years and has been marked by considerable technical innovation in both methodology and computational practicality. One area that has experienced significant growth is Bayesian methods. The growing use of Bayesian methodology has taken place partly due to an increasing number of practitioners valuing the Bayesian paradigm as matching that of scientific discovery. In addition, computational advances have allowed for more complex model...

CAUSAL INFERENCE IN STATISTICSA PrimerCausality is central to the understanding and use of data. Without an understanding of cause–effect relationships, we cannot use data to answer questions as basic as "Does this treatment harm or help patients?" But though hundreds of introductory texts are available on statistical methods of data analysis, until now, no beginner-level book has been written about the exploding arsenal of methods that can...

Bayesian Networks in R with Applications in Systems Biology is unique as it introduces the reader to the essential concepts in Bayesian network modeling and inference in conjunction with examples in the open-source statistical environment R. The level of sophistication is also gradually increased across the chapters with exercises and solutions for enhanced understanding for hands-on experimentation of the theory and concepts. The application focuses on systems biology wit...

Modern analysis of HEP data needs advanced statistical tools to separate signal from background. This is the first book which focuses on machine learning techniques. It will be of interest to almost every high energy physicist, and, due to its coverage, suitable for students.

Biostatistics with R is designed around the dynamic interplay among statistical methods, their applications in biology, and their implementation. The book explains basic statistical concepts with a simple yet rigorous language. The development of ideas is in the context of real applied problems, for which step-by-step instructions for using R and R-Commander are provided. Topics include data exploration, estimation, hypothesis testing, linear regression analysis, and clustering with two ap...

The positive reciprocal pairwise comparison matrix (PCM) is one of the key components which is used to quantify the qualitative and/or intangible attributes into measurable quantities. This book examines six understudied issues of PCM, i.e. consistency test, inconsistent data identification and adjustment, data collection, missing or uncertain data estimation, and sensitivity analysis of rank reversal. The maximum eigenvalue threshold method is proposed as the new consistency index for the...

This book is based on over a dozen years teaching a Bayesian Statistics course. The material presented here has been used by students of different levels and disciplines, including advanced undergraduates studying Mathematics and Statistics and students in graduate programs in Statistics, Biostatistics, Engineering, Economics, Marketing, Pharmacy, and Psychology. The goal of the book is to impart the basics of designing and carrying out Bayesian analyses, and interpreting and communicating...

Each passing year bears witness to the development of ever more powerful computers, increasingly fast and cheap storage media, and even higher bandwidth data connections. This makes it easy to believe that we can now – at least in principle – solve any problem we are faced with so long as we only have enough data. Yet this is not the case. Although large databases allow us to retrieve many different single pieces of information and to compute simple aggregations, general patterns and regul...

Providing a broad but in-depth introduction to neural network and machine learning in a statistical framework, this book provides a single, comprehensive resource for study and further research. All the major popular neural network models and statistical learning approaches are covered with examples and exercises in every chapter to develop a practical working understanding of the content.Each of the twenty-five chapters includes state-of-the-art descriptions and important research...

This thesis demonstrates techniques that provide faster and more accurate solutions to a variety of problems in machine learning and signal processing. The author proposes a "greedy" algorithm, deriving sparse solutions with guarantees of optimality. The use of this algorithm removes many of the inaccuracies that occurred with the use of previous models.

'Big data' poses challenges that require both classical multivariate methods and contemporary techniques from machine learning and engineering. This modern text equips you for the new world - integrating the old and the new, fusing theory and practice and bridging the gap to statistical learning. The theoretical framework includes formal statements that set out clearly the guaranteed 'safe operating zone' for the methods and allow you to assess whether data is in the zone, or near enough. ...