This book exemplifies experience across the globe in banking of cord blood, mesenchymal, embryonic and induced pluripotent stem cells for clinical use from the United States, Canada, the European Union, Switzerland and Japan to Iran, India and Serbia. The concerns are similar regardless of stem cell type or origin. Implementing core values and common standards depend often on specific circumstances of political and economic setting, which makes flexibility as important as systematic planni...

**How genomics, big data, and digital technology are revolutionizing every aspect of medicine, from physical exams to drug prescriptions to organ transplants“The Creative Destruction of Medicine should be required reading by all physicians and in all medical schools. It is simply that good.” —Forbes**Technology dominates our lives, and personal genomics is revolutionizing biology. But despite the availability of technologies that can provide virtual, perso...

"Alan Cassels strips layers of expectation, hype, jargon, false-starts, and conflicts of interest off the medical screening mantra." —Nortin M. Hadler, author of Worried SickWhy wouldn't you want to be screened to see if you're at risk for cancer, heart disease, or another potentially lethal condition? After all, better safe than sorry. Right?Not so fast, says Alan Cassels. His Seeking Sickness takes us inside the world of medical screening,...

Welcome to the world of sexed-up medicine, where patients have been turned into customers, and clinics and waiting rooms are jammed with healthy people, lured in to have their blood pressure taken and cholesterol, smear test, bowel or breast screening done. In the world of sexed-up medicine pharmaceutical companies gloss over research they don't like and charities often use dubious science and dodgy PR to 'raise awareness' of their disease, leaving a legacy of misinformation in their wake....

The Future of Drug Discovery: Who decides which diseases to treat? provides a timely and detailed look at the efforts of the pharmaceutical industry and how they relate, or should relate, to societal needs. The authors posit that as a result of increasing risk aversion and accelerated savings in research and development, the industry is not developing drugs for increasingly prevalent diseases, such as Alzheimer's disease, untreatable pain, antibiotics and more. This book carefully exposes ...

The phenomenal growth of global pharmaceutical sales and the quest for innovation are driving an unprecedented search for human test subjects, particularly in middle- and low-income countries. Our hope for medical progress increasingly depends on the willingness of the world's poor to participate in clinical drug trials. While these experiments often provide those in need with vital and previously unattainable medical resources, the outsourcing and offshoring of trials also create new prob...

Pharmacovigilance Medical Writing covers the preparation of pharmacovigilance documents for all stages of the drug development process (i.e. from clinical development through to applications for marketing authorisations to the post-marketing stage). For each document, the book presents a review of the regulatory framework that governs the content of the document, followed by practical guidance (e.g. scheduling, source data, department/functions involved in document preparation/rev...

Integrative Medicine - General Practice the Integrative Approach Series. This chapter introduces the concept of integrative medicine and the healthcare revolution. The emergence of evidence-based medicine and, more recently, evidence-based complementary medicine is challenging many previously held notions of best practice. As evidence emerges, many Western medical therapies are being confirmed as correct, or challenged as ineffective or harmful. Similarly, many complementary thera...

The Oxford Textbook of Clinical Research Ethics is the first comprehensive and systematic reference on clinical research ethics. Under the editorship of experts from the U.S. National Institutes of Health of the United States, the book's 73 chapters offer a wide-ranging and systematic examination of all aspects of research with human beings. Considering the historical triumphs of research as well as its tragedies, the textbook provides a framework for analyzing the ethical aspects of resea...

This Brief defines competitive intelligence (CI) as a tool for making investment decisions within the pharmaceutical industry. It provides an overview of processes that the regulatory affairs professional must take into account when evaluating data impacting product-based risk evaluations. These apply particularly to evaluations that focus on outputs such as regulatory approval, or the commercial impact of product labeling on the sales forecast over a limited timeframe. The Brief also prov...

Every year, hundreds of thousands of healthy volunteers and patients worldwide undertake the journey through the maze that can be clinical trials. Research participants take part in clinical trials for a variety of reasons. The healthy volunteers may be seeking extra money to pay off college tuition, or they may know someone who is suffering and would potentially benefit from the results of the trial. The patient who is terminally ill might participate in a clinical trial simply as a last ...

Over the years, medical informatics has matured into a true scientific discipline. Fundamental and applied aspects are now taught in various fields of health, including medicine, dentistry, pharmacy, nursing and public health. Medical informatics is also often included in the curricula of many other disciplines, including the life sciences, engineering and economics.Medical informatics is a complex and rapidly changing discipline. Relatively few books have been published on the sub...